Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

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http://www.wikidata.org/entity/Q27666642
Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway.Absolute quantitation of Met using mass spectrometry for clinical application: assay precision, stability, and correlation with MET gene amplification in FFPE tumor tissue.Fragment-based strategy for structural optimization in combination with 3D-QSAR.PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells.c-MET kinase inhibitors: a patent review (2011 - 2013).Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds.Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview.Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain.An engineered dimeric fragment of hepatocyte growth factor is a potent c-MET agonist.Design and synthesis of tricyclic JAK3 inhibitors with picomolar affinities as novel molecular probes.The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.Exploring c-Met kinase flexibility by sampling and clustering its conformational space.
P2860

Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met

Item
http://www.wikidata.org/entity/Q27666642
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@ast
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@en
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@nl
type
label
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@ast
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@en
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@nl
prefLabel
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@ast
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@en
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921
P932
P3181
P356
P1433
P1476
Structural basis for selective small molecule kinase inhibition of activated c-Met
@en
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921
P932