Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics - Wikidata - thesis-toulmin - TriplyDB

Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics

Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics

http://www.wikidata.org/entity/Q27679791

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A structural biology perspective on NMDA receptor pharmacology and function Structural Insights into Competitive Antagonism in NMDA Receptors Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents Stargazin promotes closure of the AMPA receptor ligand-binding domain Reduced curvature of ligand-binding domain free-energy surface underlies partial agonism at NMDA receptors.Structural dynamics of the glycine-binding domain of the N-methyl-D-aspartate receptor.Structure of an agonist-bound ionotropic glutamate receptor Emerging structural insights into the function of ionotropic glutamate receptors.Conformational transitions in the glycine-bound GluN1 NMDA receptor LBD via single-molecule FRET.Revealing an outward-facing open conformational state in a CLC Cl(-)/H(+) exchange transporter Conformational Selection and Submillisecond Dynamics of the Ligand-binding Domain of the N-Methyl-d-aspartate Receptor Molecular lock regulates binding of glycine to a primitive NMDA receptor.Prediction of N-Methyl-D-Aspartate Receptor GluN1-Ligand Binding Affinity by a Novel SVM-Pose/SVM-Score Combinatorial Ensemble Docking Scheme Computationally Discovered Potentiating Role of Glycans on NMDA Receptors.Structure and gating of tetrameric glutamate receptors.Computational Membrane Biophysics: From Ion Channels Interactions with Drugs to Cellular Function.Guidelines for the successful generation of protein-ligand complex crystals.Advancing NMDA Receptor Physiology by Integrating Multiple Approaches.NMDA receptors: linking physiological output to biophysical operation.Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling.Mechanism of partial agonism in AMPA-type glutamate receptors.Semiclosed Conformations of the Ligand-Binding Domains of NMDA Receptors during Stationary Gating.The structure-energy landscape of NMDA receptor gating.Single-molecule patch-clamp FRET microscopy studies of NMDA receptor ion channel dynamics in living cells: revealing the multiple conformational states associated with a channel at its electrical off state.Mechanism-Based Mathematical Model for Gating of Ionotropic Glutamate Receptors.The Challenge of Interpreting Glutamate-Receptor Ion-Channel Structures.Neurotransmitter Funneling Optimizes Glutamate Receptor Kinetics.NMDA Receptors in the Central Nervous System.Dynamics and allostery of the ionotropic glutamate receptors and the ligand binding domain.The LILI Motif of M3-S2 Linkers Is a Component of the NMDA Receptor Channel Gate.Activation and desensitization of ionotropic glutamate receptors by selectively triggering pre-existing motions.Unmasking GluN1/GluN3A excitatory glycine NMDA receptors

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Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics

http://www.wikidata.org/entity/Q27679791

description

2013 nî lūn-bûn

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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Conformational Analysis of NMD ...... btype-Specific Characteristics

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Conformational Analysis of NMD ...... btype-Specific Characteristics

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Conformational Analysis of NMD ...... btype-Specific Characteristics

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Conformational Analysis of NMD ...... btype-Specific Characteristics

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Conformational Analysis of NMD ...... btype-Specific Characteristics

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Conformational Analysis of NMD ...... btype-Specific Characteristics

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Anthony J Berger

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John Belcher

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Mark L Mayer

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Yongneng Yao

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P2860

Application of a Theory of Enzyme Specificity to Protein Synthesis

Improved prediction of protein side-chain conformations with SCWRL4

PHENIX: a comprehensive Python-based system for macromolecular structure solution

CHARMM: the biomolecular simulation program

Emerging models of glutamate receptor ion channel structure and function

Computational study of synthetic agonist ligands of ionotropic glutamate receptors

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR

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1788-99

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1447808

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23972471

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structural biology

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3814224

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