Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains
about
Structure and function of Gab2 and its role in cancer (Review)Nanobodies and recombinant binders in cell biologyETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formationMonobodies and other synthetic binding proteins for expanding protein scienceSelective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.Affimer proteins are versatile and renewable affinity reagentsInhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesisA New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.Specific GFP-binding artificial proteins (αRep): a new tool for in vitro to live cell applicationsFunctions of Shp2 in cancer.Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase InterfaceMonobody-mediated alteration of enzyme specificityInhibition of RAS function through targeting an allosteric regulatory site.sNASP and ASF1A function through both competitive and compatible modes of histone binding.Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways.Introduction: History of SH2 Domains and Their Applications.Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region.Targeting endogenous proteins for degradation through the affinity-directed protein missile system.Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.Facile target validation in an animal model with intracellularly expressed monobodies
P2860
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P2860
Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@ast
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@en
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@nl
type
label
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@ast
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@en
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@nl
prefLabel
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@ast
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@en
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@nl
P2093
P2860
P50
P356
P1476
Dissection of the BCR-ABL sign ...... bitors to the SHP2 SH2 domains
@en
P2093
Akiko Koide
Emel Basak Gencer
P2860
P304
P356
10.1073/PNAS.1303640110
P407
P577
2013-09-10T00:00:00Z