Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach
about
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.Design, synthesis, and pharmacological evaluation of fluorinated azoles as anti-tubercular agents.Update of Antitubercular Prodrugs from a Molecular Perspective: Mechanisms of Action, Bioactivation Pathways, and Associated Resistance.Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis.Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis.Ultrasound Assisted Synthesis of 4-(Benzyloxy)--(3-chloro-2-(substitutedphenyl)-4-oxoazetidin-1-yl) Benzamide as Challenging Anti-Tubercular ScaffoldInhA, the enoyl-thioester reductase from forms a covalent adduct during catalysis
P2860
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P2860
Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@ast
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@nl
type
label
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@ast
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@nl
prefLabel
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@ast
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@nl
P2093
P50
P921
P1476
Crystal structure of the enoyl ...... ormed by a biomimetic approach
@en
P2093
Alexandra Delbot
Aurélien Chollet
Christian Lherbet
Jean Bernadou
Lionel Mourey
Sylviane Julien
Vania Bernardes-Génisson
P304
P356
10.1016/J.JSB.2015.04.008
P577
2015-04-17T00:00:00Z