Structural basis for therapeutic inhibition of complement C5
about
Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathwaysNew milestones ahead in complement-targeted therapy.Anti-complement component 5 antibody targeting MG4 domain inhibits choroidal neovascularization.Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function.Protection of host cells by complement regulators.Structural insight into proteolytic activation and regulation of the complement system.On the state of crystallography at the dawn of the electron microscopy revolution.Gene Duplication and Protein Evolution in Tick-Host Interactions.Stratification of responders towards eculizumab using a structural epitope mapping strategy.The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins.Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation.The MFHR1 Fusion Protein Is a Novel Synthetic Multitarget Complement Inhibitor with Therapeutic Potential.Expanding horizons in complement drug discovery: challenges and emerging strategies.
P2860
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P2860
Structural basis for therapeutic inhibition of complement C5
description
2016 nî lūn-bûn
@nan
2016 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մարտին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Structural basis for therapeutic inhibition of complement C5
@ast
Structural basis for therapeutic inhibition of complement C5
@en
Structural basis for therapeutic inhibition of complement C5
@nl
type
label
Structural basis for therapeutic inhibition of complement C5
@ast
Structural basis for therapeutic inhibition of complement C5
@en
Structural basis for therapeutic inhibition of complement C5
@nl
prefLabel
Structural basis for therapeutic inhibition of complement C5
@ast
Structural basis for therapeutic inhibition of complement C5
@en
Structural basis for therapeutic inhibition of complement C5
@nl
P2093
P2860
P50
P3181
P356
P1476
Structural basis for therapeutic inhibition of complement C5
@en
P2093
Devon Sheppard
Matthijs M Jore
Miles A Nunn
Natalie M Barber
P2860
P2888
P304
P3181
P356
10.1038/NSMB.3196
P577
2016-03-28T00:00:00Z
P6179
1040479677