Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
about
Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy PhenotypeResolution advances in cryo-EM enable application to drug discovery.Structure of actomyosin rigour complex at 5.2 Å resolution and insights into the ATPase cycle mechanismStructural complexity of filaments formed from the actin and tubulin foldsThermodynamic aspects of ATP hydrolysis of actomyosin complex.Ca2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopy.High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIREWhile the revolution will not be crystallized, biochemistry reigns supreme.How Myosin Generates Force on Actin Filaments.Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.Keeping the focus on biophysics and actin filaments in Nagoya: A report of the 2016 "now in actin" symposium.Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light.Kinetic adaptation of human Myo19 for active mitochondrial transport to growing filopodia tipsNear-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation.The Shaker-1 Mouse Myosin VIIa Deafness Mutation Results in a Severely Reduced Rate of the ATP Hydrolysis Step.The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations.Catastrophic disassembly of actin filaments via Mical-mediated oxidation.Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C.Regulation of Contraction by the Thick Filaments in Skeletal Muscle.Long-range coupling between ATP-binding and lever-arm regions in myosin via dielectric allostery.Steric hindrance in the upper 50 kDa domain of the motor Myo2p leads to cytokinesis defects in fission yeast.Simultaneous refinement of inaccurate local regions and overall structure in the CASP12 protein model refinement experiment.Remodeling of Actin Filaments by Drebrin A and Its Implications.Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity.Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actin in vitro.High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.Cryo-EM structure of the bacterial actin AlfA reveals unique assembly and ATP-binding interactions and the absence of a conserved subdomain.The structure of the actin-smooth muscle myosin motor domain complex in the rigor state.Switching Muscles On and Off in Steps: The McKillop-Geeves Three-State Model of Muscle Regulation.Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells.Distinct sites in tropomyosin specify shared and isoform-specific regulation of myosins II and V.`Atomic resolution': a badly abused term in structural biology.Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy.Structural basis for cofilin binding and actin filament disassembly.Unconventional Imaging Methods to Capture Transient Structures during Actomyosin Interaction.Electron cryomicroscopy as a powerful tool in biomedical research.Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filamentsVariants in exons 5 and 6 of ACTB cause syndromic thrombocytopeniaKryo-Elektronenmikroskopie als Methode für die strukturbasierte Wirkstoffentwicklung
P2860
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P2860
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@ast
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@en
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@nl
type
label
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@ast
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@en
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@nl
prefLabel
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@ast
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@en
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
@en
P2093
Julian von der Ecken
Salma Pathan-Chhatbar
Sarah M Heissler
P2860
P2888
P3181
P356
10.1038/NATURE18295
P407
P577
2016-06-30T00:00:00Z
P6179
1026308501