Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase
about
Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2A Ras-GTPase-activating protein SH3-domain-binding proteinA novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent mannerNMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from SosCloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1The structure and function of proline-rich regions in proteinsInteraction between PAK and nck: a template for Nck targets and role of PAK autophosphorylationMutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactionsSolution Structure of Escherichia coli FeoA and Its Potential Role in Bacterial Ferrous Iron TransportX-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85β subunitStructure of an intermediate state in protein folding and aggregationThe crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loopHigh-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptidesSolution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic proteinSpecific interactions outside the proline-rich core of two classes of Src homology 3 ligandsThe SH3 domain of Eps8 exists as a novel intertwined dimerProline-rich sequences that bind to Src homology 3 domains with individual specificitiesRegulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunitUltrastructural organization of amyloid fibrils by atomic force microscopy.PRR14 is a novel activator of the PI3K pathway promoting lung carcinogenesis.NMR assignments of PI3-SH3 domain aided by protonless NMR spectroscopy.High-resolution MAS NMR analysis of PI3-SH3 amyloid fibrils: backbone conformation and implications for protofilament assembly and structure .Phosphatidylinositol 3-kinase p85{alpha} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: molecular mechanisms and biological consequences.Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case.Ligand-induced changes in dynamics in the RT loop of the C-terminal SH3 domain of Sem-5 indicate cooperative conformational coupling.T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.Interactions of phosphatidylinositol 3-kinase Src homology 3 domain with its ligand peptide studied by absorption, circular dichroism, and UV resonance raman spectroscopies.Intermolecular interactions of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase.Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing.Thermal unfolding of small proteins with SH3 domain folding pattern.Amyloid fibril formation by an SH3 domain.SH3 domain of Bruton's tyrosine kinase can bind to proline-rich peptides of TH domain of the kinase and p120cbl.Specificity of p47phox SH3 domain interactions in NADPH oxidase assembly and activation.Dynamin, endocytosis and intracellular signalling (review).The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)A binding site for SH3 domains targets dynamin to coated pits.Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation.Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteinsSH3 domains specifically regulate kinase activity of expressed Src family proteins.Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos.
P2860
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P2860
Solution structure and ligand-binding site of the SH3 domain of the p85 alpha subunit of phosphatidylinositol 3-kinase
description
1993 nî lūn-bûn
@nan
1993 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@ast
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@en
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@nl
type
label
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@ast
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@en
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@nl
prefLabel
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@ast
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@en
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@nl
P2093
P1433
P1476
Solution structure and ligand- ...... phosphatidylinositol 3-kinase
@en
P2093
A K Downing
G W Booker
I D Campbell
M D Waterfield
P C Driscoll
P304
P356
10.1016/0092-8674(93)90259-S
P407
P577
1993-05-21T00:00:00Z