Loop closure and intersubunit communication in tryptophan synthase
about
Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme proteinSignificance of two distinct types of tryptophan synthase beta chain in Bacteria, Archaea and higher plantsInfluence of the tryptophan-indole-IFNγ axis on human genital Chlamydia trachomatis infection: role of vaginal co-infectionsStructural basis for the impaired channeling and allosteric inter-subunit communication in the beta A169L/beta C170W mutant of tryptophan synthaseEntropic stabilization of the tryptophan synthase alpha-subunit from a hyperthermophile, Pyrococcus furiosus. X-ray analysis and calorimetryStructure and function of threonine synthase from yeastCrystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzymeCrystal structures of a new class of allosteric effectors complexed to tryptophan synthaseCrystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanismStructural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complexLarge conformational changes in the Escherichia coli tryptophan synthase beta(2) subunit upon pyridoxal 5'-phosphate bindingStructural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine -synthaseCrystal Structure of Escherichia coli Diaminopropionate Ammonia-lyase Reveals Mechanism of Enzyme Activation and CatalysisThermal repair of tryptophan synthase mutations in a regulatory intersubunit salt bridge. Evidence from arrhenius plots, absorption spectra, and primary kinetic isotope effects.Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase.Modelling the evolution of the archeal tryptophan synthase.A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role.Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates.Tyrosine phenol-lyase and tryptophan indole-lyase encapsulated in wet nanoporous silica gels: Selective stabilization of tertiary conformationsTwo bifunctional enzymes with ferric reduction ability play complementary roles during magnetosome synthesis in Magnetospirillum gryphiswaldense MSR-1.Switches of hydrogen bonds during ligand-protein association processes determine binding kinetics.Molecular basis defining human Chlamydia trachomatis tissue tropism. A possible role for tryptophan synthase.Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface.Substrate channelling as an approach to cascade reactions.Stochastic thermodynamics of a chemical nanomachine: The channeling enzyme tryptophan synthase.Evolution of protein complexes by duplication of homomeric interactionsThe pepsin residue glycine-76 contributes to active-site loop flexibility and participates in catalysispH dependence of tryptophan synthase catalytic mechanism: I. The first stage, the beta-elimination reaction.Allosteric communication of tryptophan synthase. Functional and regulatory properties of the beta S178P mutant.Detection of open and closed conformations of tryptophan synthase by 15N-heteronuclear single-quantum coherence nuclear magnetic resonance of bound 1-15N-L-tryptophan.Identification of the geometric requirements for allosteric communication between the alpha- and beta-subunits of tryptophan synthase.The tryptophan synthase β-subunit paralogs TrpB1 and TrpB2 in Thermococcus kodakarensis are both involved in tryptophan biosynthesis and indole salvage.Mutational scanning of a hairpin loop in the tryptophan synthase beta-subunit implicated in allostery and substrate channeling.Structure and function of the tryptophan synthase alpha(2)beta(2) complex. Roles of beta subunit histidine 86.Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.Confinement and crowding effects on tryptophan synthase α2β2complexEffect of pH and Monovalent Cations on the Formation of Quinonoid Intermediates of the Tryptophan Synthase α2β2Complex in Solution and in the CrystalSimple and inexpensive incorporation of 19F-tryptophan for protein NMR spectroscopy.Stimulated interaction between and subunits of tryptophan synthase from hyperthermophile enhances its thermal stability.Plasticity of the Tryptophan Synthase Active Site Probed by31P NMR Spectroscopy
P2860
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P2860
Loop closure and intersubunit communication in tryptophan synthase
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Loop closure and intersubunit communication in tryptophan synthase
@ast
Loop closure and intersubunit communication in tryptophan synthase
@en
Loop closure and intersubunit communication in tryptophan synthase
@nl
type
label
Loop closure and intersubunit communication in tryptophan synthase
@ast
Loop closure and intersubunit communication in tryptophan synthase
@en
Loop closure and intersubunit communication in tryptophan synthase
@nl
prefLabel
Loop closure and intersubunit communication in tryptophan synthase
@ast
Loop closure and intersubunit communication in tryptophan synthase
@en
Loop closure and intersubunit communication in tryptophan synthase
@nl
P2093
P356
P1433
P1476
Loop closure and intersubunit communication in tryptophan synthase
@en
P2093
E Gerhardt
I Schlichting
K S Anderson
T R Schneider
P304
P356
10.1021/BI9728957
P407
P577
1998-04-21T00:00:00Z