RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
about
Human metapneumovirus glycoprotein G inhibits innate immune responsesMAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesNucleic Acid sensors and type I interferon production in systemic lupus erythematosusMDA-5 recognition of a murine norovirusZ proteins of New World arenaviruses bind RIG-I and interfere with type I interferon inductionA physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infectionCrystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modificationHerpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5Immune signaling by RIG-I-like receptorsThe ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signalingIFIT1 is an antiviral protein that recognizes 5'-triphosphate RNAA novel function of human Pumilio proteins in cytoplasmic sensing of viral infectionReconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunitySuppression of the antiviral response by an influenza histone mimicZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responsesNLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathwaysRegulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteinsHepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell linesRecognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.Peroxisomes are signaling platforms for antiviral innate immunityInfluenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-IEvasion of antiviral immunity through sequestering of TBK1/IKKε/IRF3 into viral inclusion bodiesViral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activationRIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediateNegative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinaseREUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-IRiplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infectionMAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune responseRNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathwaySolution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptorsThe RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNAStructure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity responseActivation of MDA5 requires higher-order RNA structures generated during virus infectionStructure homology and interaction redundancy for discovering virus-host protein interactionsHijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responsesHuman respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-ISTING is an endoplasmic reticulum adaptor that facilitates innate immune signallingVaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7
P2860
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P2860
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@ast
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@en
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@nl
type
label
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@ast
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@en
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@nl
prefLabel
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@ast
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@en
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@nl
P2093
P50
P3181
P356
P1433
P1476
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
@en
P2093
Andreas Pichlmair
Choon Ping Tan
Oliver Schulz
Tanja I Näslund
P304
P3181
P356
10.1126/SCIENCE.1132998
P407
P577
2006-10-12T00:00:00Z