Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum
about
Safety and efficacy of co-trimoxazole for treatment and prevention of Plasmodium falciparum malaria: a systematic reviewThat Was Then But This Is Now: Malaria Research in the Time of an Eradication AgendaEvolution of resistance to sulfadoxine-pyrimethamine in Plasmodium falciparumSulphonamide resistant commensal Neisseria with alterations in the dihydropteroate synthase can be isolated from carriers not exposed to sulphonamidesApplication of genomics to field investigations of malaria by the international centers of excellence for malaria researchTransition-state inhibitors of purine salvage and other prospective enzyme targets in malariaStructural Studies of Pterin-Based Inhibitors of Dihydropteroate SynthaseCrystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroateAn optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populationsAntibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria?Mycobacterium tuberculosis folate metabolism and the mechanistic basis for para-aminosalicylic acid susceptibility and resistanceTrends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012Molecular evidence of increased resistance to anti-folate drugs in Plasmodium falciparum in North-East India: a signal for potential failure of artemisinin plus sulphadoxine-pyrimethamine combination therapyGenetic mutations in Plasmodium falciparum and Plasmodium vivax dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) in Vanuatu and Solomon Islands prior to the introduction of artemisinin combination therapyTemporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal KenyaHigh prevalence of dhfr and dhps molecular markers in Plasmodium falciparum in pregnant women of Nchelenge district, Northern ZambiaPolymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of IndiaDeclining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western EthiopiaHigh-level Plasmodium falciparum sulfadoxine-pyrimethamine resistance with the concomitant occurrence of septuple haplotype in TanzaniaCharacterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, IndiaOrigin and evolution of sulfadoxine resistant Plasmodium falciparumMultiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malariaMolecular analysis of chloroquine and sulfadoxine-pyrimethamine resistance-associated alleles in Plasmodium falciparum isolates from NicaraguaPrevalence of Plasmodium falciparum Molecular Markers of Antimalarial Drug Resistance in a Residual Malaria Focus Area in Sabah, MalaysiaTargeting purine and pyrimidine metabolism in human apicomplexan parasitesOpportunities and Challenges in Antiparasitic Drug DiscoverySulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site.Monitoring Plasmodium falciparum growth and development by UV flow cytometry using an optimized Hoechst-thiazole orange staining strategy.Mapping the origins and spread of antifolate-resistant malaria parasites.Assessment of copy number variation in genes related to drug resistance in Plasmodium vivax and Plasmodium falciparum isolates from the Brazilian Amazon and a systematic review of the literatureDiscovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assayMalaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool.Evidence of selective sweeps in genes conferring resistance to chloroquine and pyrimethamine in Plasmodium falciparum isolates in IndiaAntimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisMolecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites.High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology.Markers of anti-malarial drug resistance in Plasmodium falciparum isolates from Swaziland: identification of pfmdr1-86F in natural parasite isolatesMolecular surveillance of Plasmodium vivax dhfr and dhps mutations in isolates from Afghanistan.Plasmodium falciparum dihydrofolate reductase and dihyropteroate synthase mutations and the use of trimethoprim-sulfamethoxazole prophylaxis among persons infected with human immunodeficiency virusAllelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria
P2860
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P2860
Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum
description
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
articolo scientifico (pubblicato il 1997/12/09)
@it
artigo científico (publicado na 1997/12/09)
@pt
artículu científicu espublizáu en 1997
@ast
im Dezember 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 9 December 1997)
@en
vedecký článok (publikovaný 1997/12/09)
@sk
videnskabelig artikel (udgivet 1997/12/09)
@da
name
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@ast
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@en
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@nl
type
label
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@ast
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@en
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@nl
prefLabel
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@ast
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@en
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@nl
P2093
P2860
P3181
P356
P1476
Mutations in dihydropteroate s ...... tance in Plasmodium falciparum
@en
P2093
P2860
P304
13944-13949
P3181
P356
10.1073/PNAS.94.25.13944
P407
P577
1997-12-01T00:00:00Z