Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication
about
Biochemical analysis of human Dna2Human Dna2 is a nuclear and mitochondrial DNA maintenance proteinOkazaki fragment processing-independent role for human Dna2 enzyme during DNA replicationEnzymatic properties of the Caenorhabditis elegans Dna2 endonuclease/helicase and a species-specific interaction between RPA and Dna2A network of multi-tasking proteins at the DNA replication fork preserves genome stabilityThe MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing.Mutations in DNA replication genes reduce yeast life span.Dna2 exhibits a unique strand end-dependent helicase function.Nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity.Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation.Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityDynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiaeThe protein components and mechanism of eukaryotic Okazaki fragment maturation.On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing.A DNA2 Homolog Is Required for DNA Damage Repair, Cell Cycle Regulation, and Meristem Maintenance in Plants.Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair.Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae.Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.G-quadruplex nucleic acids and human diseaseMitochondrial helicases and mitochondrial genome maintenanceOkazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.Telomeres: structures in need of unwinding.Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase deltaThe human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants.Yet another job for Dna2: Checkpoint activation.Genetic Regulation of Dna2 Localization During the DNA Damage Response.Flap endonuclease 1 contributes to telomere stabilityThe transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells.The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivoDna2 is involved in CA strand resection and nascent lagging strand completion at native yeast telomeres.Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.Fission yeast Dna2 is required for generation of the telomeric single-strand overhangDna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.Telomere replication: poised but puzzlingDNA2-An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?Structure and Mechanisms of SF1 DNA Helicases.Four pillars of the S-phase checkpoint.Caenorhabditis elegans dna-2 is involved in DNA repair and is essential for germ-line development.A Critical Role for Dna2 at Unwound Telomeres.
P2860
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P2860
Dynamic localization of an Okazaki fragment processing protein suggests a novel role in telomere replication
description
2002 nî lūn-bûn
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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Dynamic localization of an Oka ...... l role in telomere replication
@ast
Dynamic localization of an Oka ...... l role in telomere replication
@en
Dynamic localization of an Oka ...... role in telomere replication.
@nl
type
label
Dynamic localization of an Oka ...... l role in telomere replication
@ast
Dynamic localization of an Oka ...... l role in telomere replication
@en
Dynamic localization of an Oka ...... role in telomere replication.
@nl
altLabel
Dynamic localization of an Oka ...... l role in telomere replication
@en
prefLabel
Dynamic localization of an Oka ...... l role in telomere replication
@ast
Dynamic localization of an Oka ...... l role in telomere replication
@en
Dynamic localization of an Oka ...... role in telomere replication.
@nl
P2093
P2860
P3181
P1476
Dynamic localization of an Oka ...... l role in telomere replication
@en
P2093
Judith L Campbell
Laura Hoopes
Martin Budd
Osamu Imamura
Wonchae Choe
P2860
P304
P3181
P356
10.1128/MCB.22.12.4202-4217.2002
P407
P50
P577
2002-06-01T00:00:00Z