Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.
about
SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoanAn unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decayFunctional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistanceWho Regulates Whom? An Overview of RNA Granules and Viral InfectionsSelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6How and where are nonsense mRNAs degraded in mammalian cells?The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisMutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegansQuantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombeMicrotubule disruption targets HIF-1alpha mRNA to cytoplasmic P-bodies for translational repression.Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6Analysis of the Physiological Activities of Scd6 through Its Interaction with Hmt1Nonsense-mediated mRNA decay in Tetrahymena is EJC independent and requires a protozoa-specific nucleaseHypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins.Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decayThe multiple lives of NMD factors: balancing roles in gene and genome regulationYeast hEST1A/B (SMG5/6)-like proteins contribute to environment-sensing adaptive gene expression responsesComparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathwaysIdentification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1.Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.NMD: a multifaceted response to premature translational termination.TERRA biogenesis, turnover and implications for function.RNA degradation in Saccharomyces cerevisaeNonsense-mediated mRNA decay (NMD) mechanisms.The feedback control of UPF3 is crucial for RNA surveillance in plants.Sphingolipids regulate telomere clustering by affecting the transcription of genes involved in telomere homeostasis.UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps.The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.Functional analysis of the grapevine paralogs of the SMG7 NMD factor using a heterolog VIGS-based gene depletion-complementation system.SMG1 is an ancient nonsense-mediated mRNA decay effector.The GYF domain protein PSIG1 dampens the induction of cell death during plant-pathogen interactions.Using Separation-of-Function Mutagenesis To Define the Full Spectrum of Activities Performed by the Est1 Telomerase Subunit in Vivo.The evolution and diversity of the nonsense-mediated mRNA decay pathwayCollaboration of tRNA modifications and elongation factor eEF1A in decoding and nonsense suppression
P2860
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P2860
Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@ast
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@en
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@nl
type
label
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@ast
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@en
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@nl
altLabel
Saccharomyces cerevisiae Ebs1p ...... s nonsense-mediated mRNA decay
@en
prefLabel
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@ast
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@en
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@nl
P2093
P2860
P50
P3181
P356
P1476
Saccharomyces cerevisiae Ebs1p ...... nonsense-mediated mRNA decay.
@en
P2093
Anna Deplazes
Matthias Peter
P2860
P304
P3181
P356
10.1093/NAR/GKM912
P407
P577
2007-01-01T00:00:00Z