CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation.
about
Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain.Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.Iron-dependent self-assembly of recombinant yeast frataxin: implications for Friedreich ataxia.CCC1 is a transporter that mediates vacuolar iron storage in yeast.Role of YHM1, encoding a mitochondrial carrier protein, in iron distribution of yeast.YFH1-mediated iron homeostasis is independent of mitochondrial respiration.Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis.Friedreich ataxia: from GAA triplet-repeat expansion to frataxin deficiency.Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae.A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism.Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.A genome-wide study of recombination rate variation in Bartonella henselae.The role of the Yap5 transcription factor in remodeling gene expression in response to Fe bioavailability.Genetic analysis of iron citrate toxicity in yeast: implications for mammalian iron homeostasis.Manganese homeostasis in Saccharomyces cerevisiae.Biophysical investigation of the iron in Aft1-1(up) and Gal-YAH1 Saccharomyces cerevisiae.Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent mannerMitochondrial Iron-Sulfur Cluster Activity and Cytosolic Iron Regulate Iron Traffic in Saccharomyces cerevisiae.Response to iron deprivation in Saccharomyces cerevisiae.Iron binding activity is essential for the function of IscA in iron-sulphur cluster biogenesisRegulation of cation balance in Saccharomyces cerevisiaeMethionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast.Deferiprone for the treatment of Friedreich's ataxia.Sphingolipid signaling mediates iron toxicity.Frataxin depletion in yeast triggers up-regulation of iron transport systems before affecting iron-sulfur enzyme activitiesNitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast.Yeast lacking superoxide dismutase(s) show elevated levels of "free iron" as measured by whole cell electron paramagnetic resonance.Cells lacking pfh1, a fission yeast homolog of mammalian frataxin protein, display constitutive activation of the iron starvation response.Assembly of the iron-binding protein frataxin in Saccharomyces cerevisiae responds to dynamic changes in mitochondrial iron influx and stress level.Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis.Iron toxicity in yeast: transcriptional regulation of the vacuolar iron importer Ccc1.Inhibition of heme biosynthesis prevents transcription of iron uptake genes in yeast.
P2860
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P2860
CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation.
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@ast
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@en
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@nl
type
label
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@ast
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@en
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@nl
prefLabel
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@ast
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@en
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@nl
P2860
P356
P1476
CCC1 suppresses mitochondrial ...... tochondrial iron accumulation.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.11.7626
P407
P577
2000-03-17T00:00:00Z