Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
about
Structural basis for recognition of the third SH3 domain of full-length R85 (R85FL)/ponsin by ataxin-7A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexThe Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylationThe structural plasticity of SCA7 domains defines their differential nucleosome-binding propertiesRegulation and cellular roles of ubiquitin-specific deubiquitinating enzymesCell biology of spinocerebellar ataxiaRegulated pre-mRNA splicing: the ghostwriter of the eukaryotic genomeStructural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.Sus1, Cdc31, and the Sac3 CID Region Form a Conserved Interaction Platform that Promotes Nuclear Pore Association and mRNA ExportStructural Insights into the Assembly and Function of the SAGA Deubiquitinating ModuleStructural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase ModuleA Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and ActivityMutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1.Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes.Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination.Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes.A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA.The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.Nuclear export of messenger RNAPoly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating ModuleDirect inhibition of Gcn5 protein catalytic activity by polyglutamine-expanded ataxin-7.Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes.Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.Histone acetylation, acetyltransferases, and ataxia--alteration of histone acetylation and chromatin dynamics is implicated in the pathogenesis of polyglutamine-expansion disordersCTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA.The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeastGcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression.A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polaritySus1p facilitates pre-initiation complex formation at the SAGA-regulated genes independently of histone H2B de-ubiquitylationThe tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elementsDistinct regulatory mechanisms of eukaryotic transcriptional activation by SAGA and TFIID.Functions of the proteasome on chromatin.The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction.Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.High throughput screening identifies modulators of histone deacetylase inhibitorsSUS1 introns are required for efficient mRNA nuclear export in yeastTranscriptional regulation in Saccharomyces cerevisiae: transcription factor regulation and function, mechanisms of initiation, and roles of activators and coactivators.The nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in trypanosomatids
P2860
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P2860
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@ast
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@en
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@nl
type
label
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@ast
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@en
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@nl
prefLabel
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@ast
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@en
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@nl
P2093
P2860
P356
P1433
P1476
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
@en
P2093
Ghislain G Cabal
Maren Schneider
Ulf Nehrbass
P2860
P2888
P304
P356
10.1038/NCB1733
P407
P577
2008-06-01T00:00:00Z
P5875
P6179
1010429717