Hsp90 as a Potential Therapeutic Target in Retinal Disease

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HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness.Recent advances in uveal melanoma treatment.

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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2016 nî lūn-bûn

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2016 թուականին հրատարակուած գիտական յօդուած

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2016 թվականին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

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Mònica Aguilà

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Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

Structural and functional impairment of endocytic pathways by retinitis pigmentosa mutant rhodopsin-arrestin complexes

Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.

Geldanamycin, a HSP90 inhibitor, attenuates the hypoxia-induced vascular endothelial growth factor expression in retinal pigment epithelium cells in vitro.

A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas.

Novel isoforms of heat shock transcription factor 1, HSF1γα and HSF1γβ, regulate chaperone protein gene transcription.

Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration

Hsp90 inhibition protects against inherited retinal degeneration.

Consequences of oxidative stress in age-related macular degeneration.

The cell stress machinery and retinal degeneration.

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161-167

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scholarly article

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10.1007/978-3-319-17121-0_22

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English

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854

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Michael E. Cheetham

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2016-01-01T00:00:00Z

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26427407

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5044979

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Hsp90 as a Potential Therapeutic Target in Retinal Disease

about

P2860

P2860

Hsp90 as a Potential Therapeutic Target in Retinal Disease

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P478

P50

P577

P698

P932