about
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Alternative end-joining mechanisms: a historical perspectiveKu binds telomeric DNA in vitroTIN2, a new regulator of telomere length in human cellsInteraction of human Ku70 with TRF2Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresThe telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)ORC binding to TRF2 stimulates OriP replicationTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2PTOP interacts with POT1 and regulates its localization to telomeresProtein requirements for sister telomere association in human cellsFive dysfunctional telomeres predict onset of senescence in human cellsFeedback between p21 and reactive oxygen production is necessary for cell senescenceTelomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicasesTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsWRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shorteningTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationSIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatinIn vivo stoichiometry of shelterin componentsTRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwindingTRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent mannerPinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesTelomere protection by mammalian Pot1 requires interaction with Tpp1Characterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesThe human Rap1 protein complex and modulation of telomere lengthPoly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progressionPOT1 and TRF2 cooperate to maintain telomeric integrityhnRNP A2, a potential ssDNA/RNA molecular adapter at the telomereMammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicingControl of human telomere length by TRF1 and TRF2Smurf2 up-regulation activates telomere-dependent senescenceHuman Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpointFunctional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationCharacterization of the yeast telomere nucleoprotein core: Rap1 binds independently to each recognition siteCrisis intervention: the role of telomeraseHuman heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiationTelomere protection by TPP1 is mediated by POT1a and POT1b
P2860
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P2860
description
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Februar 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998-02)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd in 1998-02)
@nl
наукова стаття, опублікована в лютому 1998
@uk
مقالة علمية (نشرت في فبراير 1998)
@ar
name
TRF2 Protects Human Telomeres from End-to-End Fusions
@ast
TRF2 Protects Human Telomeres from End-to-End Fusions
@en
TRF2 protects human telomeres from end-to-end fusions
@nl
type
label
TRF2 Protects Human Telomeres from End-to-End Fusions
@ast
TRF2 Protects Human Telomeres from End-to-End Fusions
@en
TRF2 protects human telomeres from end-to-end fusions
@nl
altLabel
TRF2 protects human telomeres from end-to-end fusions
@en
prefLabel
TRF2 Protects Human Telomeres from End-to-End Fusions
@ast
TRF2 Protects Human Telomeres from End-to-End Fusions
@en
TRF2 protects human telomeres from end-to-end fusions
@nl
P50
P3181
P1433
P1476
TRF2 Protects Human Telomeres from End-to-End Fusions
@en
TRF2 protects human telomeres from end-to-end fusions
@en
P2093
A. Smogorzewska
B. van Steensel
P3181
P356
10.1016/S0092-8674(00)80932-0
P407
P577
1998-02-01T00:00:00Z
1998-02-06T00:00:00Z