Integrins αvβ3 and α4β1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1
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Analysis of the Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Traumatic Brain and Spinal Cord Injury: Insight into Recent Advances in Actions of Neurochemokine Agents.Cytoskeletal confinement of CX3CL1 limits its susceptibility to proteolytic cleavage by ADAM10The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site.Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.Snake Venom Disintegrin Inhibits the Activation of Toll-Like Receptors and Alleviates Sepsis through Integrin alphaVbeta3 Blockade.An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.Modulation of platelet and monocyte function by the chemokine fractalkine (CX3 CL1) in cardiovascular disease.The influence of stromal cells and tumor-microenvironment-derived cytokines and chemokines on CD3+CD8+ tumor infiltrating lymphocyte subpopulations.Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1.The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis.Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling.Microglia, seen from the CX3CR1 angle.Direct binding to integrins and loss of disulfide linkage in interleukin-1β (IL-1β) are involved in the agonistic action of IL-1β.Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner.
P2860
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P248
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P2860
Integrins αvβ3 and α4β1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1
description
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Dezember 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2012/12/15)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/12/15)
@nl
наукова стаття, опублікована в грудні 2012
@uk
مقالة علمية (نشرت في 15-12-2012)
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name
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
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Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
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Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
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type
label
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
@ast
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
@en
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
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prefLabel
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
@ast
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
@en
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
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P2860
P921
P356
P1476
Integrins αvβ3 and α4β1 act as ...... ine is an antagonist of CX3CR1
@en
P2093
Masaaki Fujita
Yoko K. Takada
P2860
P304
P356
10.4049/JIMMUNOL.1200889
P407
P577
2012-12-15T00:00:00Z