about
Coupling of human circadian and cell cycles by the timeless protein.Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clockTipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint functionFunctional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in miceTranscriptional oscillation of canonical clock genes in mouse peripheral tissuesCircadian rhythms from flies to humanUpregulation of human mitochondrial NADH dehydrogenase subunit 5 in intestinal epithelial cells is modulated by Vibrio cholerae pathogenesisMammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factorsMop3 is an essential component of the master circadian pacemaker in mammalsMammalian circadian biology: elucidating genome-wide levels of temporal organizationIndividual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis.An unexpected role for the clock protein timeless in developmental apoptosisGenetic variation of clock genes and cancer risk: a field synopsis and meta-analysisCircadian Clock, Cell Division, and Cancer: From Molecules to Organism.Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.Flies, clocks and evolution.Central clock regulates the cervically stimulated prolactin surges by modulation of dopamine and vasoactive intestinal polypeptide release in ovariectomized rats.Comparing clockworks: mouse versus fly.Transcriptome comparison between fetal and adult mouse livers: implications for circadian clock mechanismsInvited review: Sleeping flies don't lie: the use of Drosophila melanogaster to study sleep and circadian rhythms.Molecular regulation of circadian rhythms in Drosophila and mammals.The intra-S phase checkpoint protein Tof1 collaborates with the helicase Rrm3 and the F-box protein Dia2 to maintain genome stability in Saccharomyces cerevisiae.Invited review: regulation of mammalian circadian clock genes.Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signalingCircadian clock, cancer, and chemotherapy.Molecular and phylogenetic analyses reveal mammalian-like clockwork in the honey bee (Apis mellifera) and shed new light on the molecular evolution of the circadian clockGetting a buzz out of the bee genome.TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival.TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage ResponseTranscription regulation within the circadian clock: the E-box and beyond.Clock gene evolution and functional divergence.Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts.Caenorhabditis elegans opens up new insights into circadian clock mechanisms.Molecular genetics of the fruit-fly circadian clock.Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblastsMolecular circadian rhythms in central and peripheral clocks in mammals.The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity.Tumor suppression and circadian function.A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta.
P2860
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P2860
description
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
scientific article (publication date: August 2000)
@en
vedecký článok (publikovaný 2000-08)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd in 2000-08)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в серпні 2000
@uk
مقالة علمية (نشرت في أغسطس 2000)
@ar
name
A time-less function for mouse timeless
@ast
A time-less function for mouse timeless
@en
A time-less function for mouse timeless
@nl
type
label
A time-less function for mouse timeless
@ast
A time-less function for mouse timeless
@en
A time-less function for mouse timeless
@nl
prefLabel
A time-less function for mouse timeless
@ast
A time-less function for mouse timeless
@en
A time-less function for mouse timeless
@nl
P2093
P356
P1433
P1476
A time-less function for mouse timeless
@en
P2093
A L Gotter
B Possidente
D R Weaver
D T MacLaughlin
L F Kolakowski
S M Reppert
T Manganaro
P2888
P356
10.1038/77653
P407
P577
2000-08-01T00:00:00Z