The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7
about
Evolution of the relaxin-like peptide familyR-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signalingConstitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi networkLGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressorThyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptorBursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distensionRelaxin family peptide receptors--former orphans reunite with their parent ligands to activate multiple signalling pathwaysInternational Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligandsLGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signalingCross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors.In a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR FamilyLGR4 and Its Role in Intestinal Protection and Energy MetabolismRole of the Extracellular and Intracellular Loops of Follicle-Stimulating Hormone Receptor in Its FunctionAdult mammalian stem cells: the role of Wnt, Lgr5 and R-spondinsLgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions.The structural basis of R-spondin recognition by LGR5 and RNF43Structural basis for R-spondin recognition by LGR4/5/6 receptorsCrystal Structures of Lgr4 and Its Complex with R-Spondin1The human LGR7 low-density lipoprotein class A module requires calcium for structureIncreased expression of the relaxin receptor (LGR7) in human endometrium during the secretory phase of the menstrual cycleSplice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexityLgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in miceImpaired nipple development and parturition in LGR7 knockout miceOrigin of INSL3-mediated testicular descent in therian mammalsCrystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsGPCR genes are preferentially retained after whole genome duplicationDistinct high-profile methylated genes in colorectal cancerRelaxin gene family in teleosts: phylogeny, syntenic mapping, selective constraint, and expression analysis.Relaxin-Family Peptide Receptors 1 and 2 Are Fully Functional in the Bovine.Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophoreOrphan G protein-coupled receptors (GPCRs): biological functions and potential drug targetsTranscriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathwaysA naturally occurring Lgr4 splice variant encodes a soluble antagonist useful for demonstrating the gonadal roles of Lgr4 in mammals.Functional differences of invariant and highly conserved residues in the extracellular domain of the glycoprotein hormone receptorsThe human relaxin receptor (LGR7): expression in the fetal membranes and placenta.LGR5 promotes the proliferation and tumor formation of cervical cancer cells through the Wnt/β-catenin signaling pathway.Relaxin induces matrix-metalloproteinases-9 and -13 via RXFP1: induction of MMP-9 involves the PI3K, ERK, Akt and PKC-ζ pathways
P2860
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P2860
The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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The three subfamilies of leuci ...... e signaling mechanism for LGR7
@ast
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@en
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@nl
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label
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@ast
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@en
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@nl
prefLabel
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@ast
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@en
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@nl
P2093
P356
P1476
The three subfamilies of leuci ...... e signaling mechanism for LGR7
@en
P2093
K Nakabayashi
M van Duin
P J van der Spek
P304
P356
10.1210/MEND.14.8.0510
P407
P577
2000-08-01T00:00:00Z