A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system
about
The cytoskeletal protein Ndel1 regulates dynamin 2 GTPase activityRole of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore functionLIS1, CLIP-170's key to the dynein/dynactin pathway.Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity.Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylationRefinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assemblyDisrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowthHuman Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindleInhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1Treacher Collins syndrome: etiology, pathogenesis and preventionFunctional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophreniaNudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dyneinNeuroanatomical phenotypes in the reeler mouseSevere NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stagesCytoskeleton Molecular Motors: Structures and Their Functions in NeuronMolecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical DevelopmentNeuronal migration abnormalities and its possible implications for schizophreniaExtra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disordersNeuronal migration and its disorders affecting the CA3 regionCSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid FormationRegulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration.Nudel and FAK as antagonizing strength modulators of nascent adhesions through paxillinUNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons.Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans.Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast.NudEL targets dynein to microtubule ends through LIS1.14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndromeThe DISC locus in psychiatric illnessA frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorderRegulators of the cytoplasmic dynein motorDISC1-binding proteins in neural development, signalling and schizophreniaA Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells.Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway.SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in miceTargeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerizationLIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages
P2860
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P2860
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@ast
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@en
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@nl
type
label
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@ast
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@en
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@nl
prefLabel
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@ast
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@en
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@nl
P2093
P921
P3181
P1433
P1476
A LIS1/NUDEL/cytoplasmic dynei ...... oping and adult nervous system
@en
P2093
A Shionoya
A Wynshaw-Boris
J Yingling
M J Gambello
S Hirotsune
P304
P3181
P356
10.1016/S0896-6273(00)00146-X
P407
P577
2000-12-01T00:00:00Z