Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)
about
Clinical use of crizotinib for the treatment of non-small cell lung cancerALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistanceWill the Requirement by the US FDA to Simultaneously Co-Develop Companion Diagnostics (CDx) Delay the Approval of Receptor Tyrosine Kinase Inhibitors for RTK-Rearranged (ROS1-, RET-, AXL-, PDGFR-α-, NTRK1-) Non-Small Cell Lung Cancer Globally?ROS1 rearrangements define a unique molecular class of lung cancers.Crizotinib in ROS1-rearranged non-small-cell lung cancer.PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutationsTesting for ROS1 in non-small cell lung cancer: a review with recommendationsTargeted Therapies in Non-Small Cell Lung Cancer-Beyond EGFR and ALKFrom single-gene to multiplex analysis in lung cancer, challenges and accomplishments: a review of a single institution's experience.Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer typesSpectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokersTransforming fusions of FGFR and TACC genes in human glioblastoma.Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number dataFluorescence in situ hybridization in surgical pathology: principles and applications.Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinomaChromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours.Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies.PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.Current concepts on the molecular pathology of non-small cell lung carcinoma.Molecular pathways: ROS1 fusion proteins in cancer.Activation of RAS family members confers resistance to ROS1 targeting drugs.Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions.Mouse model for ROS1-rearranged lung cancerOncogenic gene fusions in epithelial carcinomasDiscovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation.Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.Activated RET and ROS: two new driver mutations in lung adenocarcinoma.Tumor-specific mutations in low-frequency genes affect their functional properties.Lack of ROS1 Gene Rearrangement in Glioblastoma MultiformeClinical and pathological significance of ROS1 expression in intrahepatic cholangiocarcinomaNovel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.Genetic and biochemical alterations in non-small cell lung cancer.KAOS: a new automated computational method for the identification of overexpressed genes.Deciphering the Key Features of Malignant Tumor Microenvironment for Anti-cancer TherapySynergistic Effects of Crizotinib and Temozolomide in Experimental FIG-ROS1 Fusion-Positive Glioblastoma.PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patientsCrizotinib for the treatment of ALK-rearranged non-small cell lung cancer: a success story to usher in the second decade of molecular targeted therapy in oncologyROS1 expression in invasive ductal carcinoma of the breast related to proliferation activity.Personalizing therapy in advanced non-small cell lung cancer
P2860
Q24630466-449783FD-3015-4E12-8BE1-9A57D8591557Q26775347-A2D3D939-3D6D-4802-A0E9-794E66CCF348Q27023383-98D9C974-2506-4AEC-B672-52AD2E80E1BAQ27851700-6F0C1EEB-3368-42CC-B4E7-778BC7B55BF6Q27853075-183B1D01-10E4-4798-B061-34339D27AD93Q27853138-EFB31654-3E83-494B-926B-D11203D5680EQ28070062-FBE612C6-1544-4137-96F5-673451933B35Q28083446-1B6E70A6-8B26-43CA-84F5-59D7EEFE5F94Q28385559-1E960FE6-0EED-415A-9905-943FC74860A2Q28486949-6E7D2A26-6838-4381-9134-9A0CAE7754F2Q28742090-B310E1E7-7CED-4083-B8A6-36A46F932477Q30540467-93DFA911-A009-4AC0-8B9A-A385BD4A0EF8Q30699293-F2066F6E-7E0C-4CB9-A8F9-50E6CEF709EBQ33593910-673FC594-25CE-41CF-8E62-CD86083CD550Q33799157-AF27A3B8-A589-45A2-A99C-0DE785ED188EQ34097804-78E813BD-562C-4C41-B800-46A193855102Q34132781-C75D5407-470B-4579-AB31-7B04E7C689DCQ34164924-54B5EAE0-5A4C-450E-B56E-91C277B684B3Q34295696-FF200277-F030-408D-BC9E-F54F613B6E2AQ34310062-858562F7-1965-42ED-AD97-6A0DE03C7EBCQ34347504-CBCF1AEC-9567-4E30-A5B7-08D1E84C5724Q34463388-3C7B34FC-5F1B-4DBA-A09D-C2693E202F41Q34522899-E948C053-4C37-4F2F-930C-1D3BF1DFC2C0Q34589721-7F7E046A-3A2A-43C4-B203-24554615E78BQ34949690-655507D6-3CBD-4AA7-A6AB-7CDDCB0C8A39Q35080328-4D98E9F6-9C41-4D0C-A818-1CB73E378E6AQ35145481-34C32A67-01DF-418A-ADD6-7B1DCF4DB709Q35206630-022FF8BC-7417-4CBE-A8D2-79AA9E9B1839Q35621520-BAB8BCBB-2862-4F28-80DD-32CF2DD9254FQ35772397-4CD1B060-E659-44D6-8D89-2BCC2FCC4EBFQ35811132-6AB194B6-2C5B-4F57-87EC-297D591CA72DQ35999416-568A843E-4A60-4849-9F78-B28581E352A4Q36184584-FCD349E3-2425-4A4E-94DC-2EBF562B0A90Q36276385-62176FFD-B6FE-4ECD-912E-6809E0818803Q36284940-2B0C3374-504F-4B7E-9A0F-03781949237AQ36341179-4E982640-C046-46F3-A4E7-A34A326E9FA2Q36402259-10195DDD-CA34-432D-99AD-BE1166660409Q36405628-9C47658E-863B-4CAA-A0DB-653105D230E2Q36793176-0F714500-DF43-4C7E-8023-67F8FE07E980Q36811453-A86B5698-F01B-4831-9F1D-CDF4EF3C09C0
P2860
Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@ast
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@en
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@nl
type
label
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@ast
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@en
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@nl
prefLabel
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@ast
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@en
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@nl
P2093
P3181
P356
P1476
Fusion of FIG to the receptor ...... an interstitial del(6)(q21q21)
@en
P2093
Alain Charest
David Housman
Elizabeth Preisinger
Julie Park
Keara Lane
Kevin McMahon
P3181
P356
10.1002/GCC.10207
P407
P50
P577
2003-05-01T00:00:00Z