Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers - Wikidata - thesis-toulmin - TriplyDB

Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers

Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers

http://www.wikidata.org/entity/Q28206723

about

sameAs

The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia Guidance molecules in lung cancer The emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancers Netrin-1 and its receptors in tumorigenesis ROBO1, a tumor suppressor and critical molecular barrier for localized tumor cells to acquire invasive phenotype: study in African-American and Caucasian prostate cancer models The role of DNA methylation as biomarkers in the clinical management of lung cancer.MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor.Down-regulation of ROBO2 expression in prostate cancers Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes.Identification of methylated genes associated with aggressive clinicopathological features in mantle cell lymphoma.Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis.Inactivation of SLIT2-ROBO1/2 pathway in premalignant lesions of uterine cervix: clinical and prognostic significances Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression Expression and roles of Slit/Robo in human ovarian cancer.Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma.Low Expression of Slit2 and Robo1 is Associated with Poor Prognosis and Brain-specific Metastasis of Breast Cancer Patients The Slit receptor Robo1 is predominantly expressed via the Dutt1 alternative promoter in pioneer neurons in the embryonic mouse brain and spinal cord.Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway.Whole-exome and targeted sequencing identify ROBO1 and ROBO2 mutations as progression-related drivers in myelodysplastic syndromes.Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness.SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics A roundabout way to cancer.DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.Function of Slit/Robo signaling in breast cancer.Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers.The epigenetic landscape of renal cancer.Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma.Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches.Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma Frequent alterations of SLIT2-ROBO1-CDC42 signalling pathway in breast cancer: clinicopathological correlation.Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.Frequent epigenetic inactivation of the SLIT2 gene in gliomas.A mutational comparison of adult and adolescent and young adult (AYA) colon cancer.Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer.Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.Multiple locations on chromosome 3 are the targets of specific deletions in uveal melanoma.Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.Robo1 and vimentin regulate radiation-induced motility of human glioblastoma cells.

P2860

Q21092504-75443A3C-3D49-4207-8BB7-7E85502B54CF Q24598659-E17E054A-B73D-409E-9F50-365139DA0027 Q26775454-DA702D8D-1C47-4189-BF69-313D5EFFF8D6 Q28295909-70F2FA09-9686-4025-BC90-C7461D7C6B62 Q30009431-3AE7B48E-DC3A-43D2-AC11-0C31AB421AAC Q30317739-58423AF6-BB7A-4778-AF14-946BC903D631 Q33543185-00E4D5A4-82DD-4587-9C8F-F9C157003CD0 Q33775077-26D0A6C3-5517-455F-A81F-F8A426FF1E76 Q33853031-A524AE83-FD33-4856-98D1-5F7AAE060FB6 Q33908446-B8B66B50-3A3B-4B2A-A6AE-9196396D2CF0 Q33947900-F2177CCB-976E-4F32-839C-79B9EA2ABB2D Q34311871-FFC0F668-0DD1-4AE5-A1FA-5C6B96C2DD4A Q34695790-8FB09F83-1326-45D9-95EA-E6C9383F206B Q35759877-4CB9259C-B5EE-4F41-82DC-8408C1672B64 Q35911266-045B69BB-4C62-4757-95D5-7F358E7E4324 Q36099714-7E5358DB-0FE8-495E-B800-B3E1F4337BE9 Q36149114-981AD6EA-D4EF-43DC-AFE3-E6F65D4007ED Q36243638-1E636F28-E725-468E-BD7C-D0FABB0553DA Q36360964-B378BA28-B7BA-4D89-A7B4-57E34429376C Q36687634-CD66D694-5A1E-44F8-8F62-3300069118A3 Q36694377-946B3264-59E7-4B8B-A04F-F6A1038AD3E6 Q37785109-A50B357E-54CD-4453-8852-A57580C12585 Q38010295-352BF393-E4A9-4BCF-805B-EB2BF4C9A188 Q38296215-F1A30822-B91A-4188-8E5B-9B24B960A0FC Q38626660-397A2D85-8131-4538-BB47-4CF9178EBA75 Q38799612-96FB3A18-A4AF-44DF-BA6D-BD1B4709ACC9 Q39021700-333A840B-EF8F-443D-89C6-D88813278F7F Q39739609-124A4909-BFBD-4F39-B9F4-1E3DBEBFB42D Q39821255-F4BBEA39-A09A-4371-9E51-D431D27C3AD5 Q40025069-07C4E86A-66A3-4006-A647-A58DA90FF9E2 Q40569399-32DDAC79-E5C3-430C-8A9A-4E4BF17CE6D1 Q41817195-7ABC8D28-05F9-4B2F-963F-2C7E37126A14 Q43062776-873C4399-AFF6-4F1B-A3E2-98EB6F1483B3 Q44526180-C07621C9-A8AE-4BD6-8BA6-49C12A8BBB8B Q47342245-34EE56FD-93A0-49D7-B1AB-ABD0856EB78D Q49544302-2F6AB543-A68D-4E9D-A17E-218ACD2586A5 Q52561250-BB8792AE-D8FE-40FE-B8D1-E5E4B19A61B0 Q52564461-9786FFF0-AE1D-4898-99DF-C24CE34CA388 Q53242589-3B9096E2-CDE9-4C83-A2DD-691E39C44006 Q54977184-5F9BE48B-00FD-4891-8567-250B67C7AEFA

P2860

Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers

http://www.wikidata.org/entity/Q28206723

description

2002 nî lūn-bûn

@nan

2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@ast

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@en

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@nl

type

label

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@ast

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@en

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@nl

prefLabel

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@ast

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@en

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@nl

P1433

Q28206723-4A097422-9AED-4F14-B301-FF3C732E9BF1

P1476

Q28206723-E920AF56-65EE-4F69-A289-987B3611B5DF

P2093

Q28206723-1CBB9A22-D9D7-4A08-A1EC-5EC45DD86F27

Q28206723-49610292-C636-4DA8-9A12-0330ABCAC8A8

Q28206723-50CD141E-EB66-4F2B-A18D-C6DC5E839339

Q28206723-5A01FAD8-2F05-4374-B96D-D78483AB182D

Q28206723-A5832780-DBBB-4757-BC5B-B3D2A85A3E61

Q28206723-ADCDC003-EC75-4D01-8FB8-D9430061D8B8

Q28206723-AF2346DC-99B1-4E96-B11A-06D82B9AC1AC

Q28206723-AFF618F0-AB70-41C3-892D-834D4D39F5A1

Q28206723-C1457811-682A-44C0-AA48-B99809D2F228

Q28206723-FA2EF08A-0211-43BC-B717-EC09132B41CD

P2860

Q28206723-05036E14-1CE5-461B-9ADD-87599F29EBC7

Q28206723-05576070-8FCC-4775-9E02-EAB1C677E651

Q28206723-2B8BA851-82D2-4AD0-B67A-8F65BEA6C487

Q28206723-2FE2216A-CD54-4529-924B-0AECEE0DC637

Q28206723-3E7FBCD7-15CB-4CB7-9ABE-051377975E3C

Q28206723-484B0AB2-1DA1-443A-AEE7-AE59C8E98750

Q28206723-56540E36-E0E6-402A-96B2-9779E2D1AE8D

Q28206723-5756C4A0-F208-419F-8466-DB19A4DCBA05

Q28206723-5AC3A8C9-D17E-434F-A749-D084C1728995

Q28206723-5E107D43-8824-4CD3-9689-17CDE280EEC3

P2888

Q28206723-D00F1E03-89C4-460F-9E71-F7C938B9277C

P304

Q28206723-F4F20F33-A29B-4009-9DDA-46AC5BE42601

P31

Q28206723-41EFC044-6C93-473E-8425-782DE783F33C

P356

Q28206723-49FA21B7-E669-4663-8F26-91FC4DE0A76C

P407

Q28206723-96D91802-4584-483F-BF61-2F236747E642

P433

Q28206723-C3CCE60C-2C31-4DEA-93A8-F56FDB1AF248

P478

Q28206723-5F1C9731-1EFE-48B7-874F-83B9EE6942B4

P577

Q28206723-490A95B0-6ABD-4F1B-962D-F23E4E8A49ED

P5875

Q28206723-26D144FB-4B25-42D3-9C47-5DF7E6466675

P6179

Q28206723-AABE3F06-2B6B-4DC7-B8EC-FDE6323EA107

P698

Q28206723-9BB1C204-1949-4BBE-89E2-72775DCB3A44

P921

Q28206723-E9F3744A-0B3C-45E4-BCAE-D5FB84C31D73

P356

P1433

P1476

Tumour specific promoter regio ...... DUTT1 (ROBO1) in human cancers

@en

P2093

Alonso Martinez

http://www.w3.org/2001/XMLSchema#string

Ashraf Dallol

http://www.w3.org/2001/XMLSchema#string

Eamonn R Maher

http://www.w3.org/2001/XMLSchema#string

Eva Forgacs

http://www.w3.org/2001/XMLSchema#string

Farida Latif

http://www.w3.org/2001/XMLSchema#string

John D Minna

http://www.w3.org/2001/XMLSchema#string

Pamela Rabbitts

http://www.w3.org/2001/XMLSchema#string

Rosemary Walker

http://www.w3.org/2001/XMLSchema#string

Takeshi Kishida

http://www.w3.org/2001/XMLSchema#string

Yoshitaka Sekido

http://www.w3.org/2001/XMLSchema#string

P2860

Involvement of chemokine receptors in breast cancer metastasis

The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression

Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex

Homozygous deletions at 3p12 in breast and lung cancer

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

P2888

P304

3020-8

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1205421

http://www.w3.org/2001/XMLSchema#string

P407

P433

19

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P577

2002-05-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11291822

http://www.w3.org/2001/XMLSchema#string

P6179

1050702382

http://www.w3.org/2001/XMLSchema#string

P698

12082532

http://www.w3.org/2001/XMLSchema#string

P921