The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
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From dynamic expression patterns to boundary formation in the presomitic mesodermThe F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevisSIRT2 induces the checkpoint kinase BubR1 to increase lifespanThe stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γSEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide productionFbxw7 regulates lipid metabolism and cell fate decisions in the mouse liverFAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7Nuclear signalling by tumour-associated antigen EpCAMPhosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligaseMastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complexSCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysisThe cilia-regulated proteasome and its role in the development of ciliopathies and cancerNotch Signaling in Neuroendocrine TumorsNotch signaling: its roles and therapeutic potential in hematological malignanciesThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaThe role of targeted protein degradation in early neural developmentTargeting the ubiquitin pathway for cancer treatmentGenome-Wide Identification and Expression of Xenopus F-Box Family of ProteinsExpression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational controlc-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-FmsTip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylationInsulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)Notch signalling: a simple pathway becomes complexTurn It Down a NotchGamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptorhnRNP I inhibits Notch signaling and regulates intestinal epithelial homeostasis in the zebrafish.Mutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegansMinireview: thyroid hormone transporters: the knowns and the unknowns.FBXW7 mutations in melanoma and a new therapeutic paradigmThe p75 neurotrophin receptor localization in blood-CSF barrier: expression in choroid plexus epitheliumNuclear retention of Fbw7 by specific inhibitors of nuclear export leads to Notch1 degradation in pancreatic cancerInteraction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs.Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibilityMammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma.Notch inhibitors for cancer treatment.Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence.
P2860
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P2860
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@ast
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@en
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@nl
type
label
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@ast
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@en
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@nl
prefLabel
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@ast
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@en
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@nl
P2093
P3181
P356
P1476
The Notch intracellular domain ...... y the mammalian Sel-10 homolog
@en
P2093
P304
P3181
P356
10.1074/JBC.M103992200
P407
P577
2001-09-21T00:00:00Z