Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
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Screening of functional and positional candidate genes in families with common variable immunodeficiencySelective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative diseaseFollicular helper T cells: lineage and locationCD20 deficiency in humans results in impaired T cell-independent antibody responsesThe costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cellsRole for Msh5 in the regulation of Ig class switch recombinationAltered dendritic cell distribution in patients with common variable immunodeficiency.T-cell abnormalities in common variable immunodeficiency: the hidden defectCan follicular helper T cells be targeted to improve vaccine efficacy?International Consensus Document (ICON): Common Variable Immunodeficiency DisordersSeronegative Celiac Disease and Immunoglobulin Deficiency: Where to Look in the Submerged Iceberg?A brief history of T cell help to B cellsHumoral immunodeficiency : awareness for better supportComparison of diagnostic criteria for common variable immunodeficiency disorderDeleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunityTh17 effector cells support B cell responses outside of germinal centrescDNA Sequence and Fab Crystal Structure of HL4E10, a Hamster IgG Lambda Light Chain Antibody Stimulatory for γδ T CellsICOS Co-Stimulation: Friend or Foe?Unbalanced Immune System: Immunodeficiencies and AutoimmunityEducational paper: primary antibody deficienciesUpdate in understanding common variable immunodeficiency disorders (CVIDs) and the management of patients with these conditionsGermline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiencyA RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunityAP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signalingAnalysis of families with common variable immunodeficiency (CVID) and IgA deficiency suggests linkage of CVID to chromosome 16qGranulomatous disease in common variable immunodeficiency.Autoimmune cytopenias in common variable immunodeficiency.Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cellsCommon variable immunodeficiency: etiological and treatment issues.Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection.Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVIDB7h is required for T cell activation, differentiation, and effector function.CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency.The many faces of common variable immunodeficiency.Protective effector memory CD4 T cells depend on ICOS for survival.Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection.A novel ICOS-independent, but CD28- and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine.The clinical utility of molecular diagnostic testing for primary immune deficiency disorders: a case based review.How I treat common variable immune deficiency.Toll-like receptor 7 and 9 defects in common variable immunodeficiency.
P2860
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P2860
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@ast
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@en
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@nl
type
label
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@ast
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@en
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@nl
prefLabel
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@ast
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@en
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@nl
P2093
P3181
P356
P1433
P1476
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
@en
P2093
Alejandro A Schäffer
Beate Fischer
Bodo Grimbacher
Erik Glocker
Hans H Peter
Hans W Mages
Hermann Eibel
Klaus Warnatz
Michael Schlesier
Richard A Kroczek
P3181
P356
10.1038/NI902
P407
P577
2003-03-01T00:00:00Z