Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
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Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in miceTissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agentReceptor specificity of the fibroblast growth factor family. The complete mammalian FGF familyMolecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily membersEndocrine FGFs: Evolution, Physiology, Pathophysiology, and PharmacotherapyMiscellaneous non-inflammatory musculoskeletal conditions. Hyperphosphatemic familial tumoral calcinosis (FGF23, GALNT3 and αKlotho)Fibroblast growth factor 23FGF23 and Phosphate Wasting DisordersSkeletal secretion of FGF-23 regulates phosphate and vitamin D metabolismRegulation and function of the FGF23/klotho endocrine pathwaysFibroblast Growth Factor 23: A New Dimension to Diseases of Calcium-Phosphorus MetabolismRole of FGF23 in vitamin D and phosphate metabolism: implications in chronic kidney diseaseExploring mechanisms of FGF signalling through the lens of structural biologyProtective roles of DMP1 in high phosphate homeostasisA potential link between phosphate and aging--lessons from Klotho-deficient miceFibroblast Growth Factor-23-A Potential Uremic ToxinThe secretory pathway kinasesThe autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potencyHuman fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 productionProteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemiaMolecular mechanisms of fibroblast growth factor signaling in physiology and pathologyRationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 DiabetesRegulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemiaOsteocyte-specific deletion of Fgfr1 suppresses FGF23Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporterRegulation of fibroblast growth factor-23 signaling by klothoRegulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null miceTargeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolismFibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolismNovel bone endocrine networks integrating mineral and energy metabolismIsolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically activeFGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts.The use of fibroblast growth factor 23 testing in patients with kidney disease.Vitamin D: metabolism.Fibroblast growth factor-23 increases mouse PGE2 production in vivo and in vitro.FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.
P2860
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P2860
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@ast
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@en
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@nl
type
label
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@ast
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@en
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@nl
prefLabel
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@ast
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@en
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@nl
P2093
P3181
P1433
P1476
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
@en
P2093
A Benet-Pages
B Lorenz-Depiereux
P304
P3181
P356
10.1046/J.1523-1755.2001.00064.X
P407
P577
2001-12-01T00:00:00Z
P5875
P6179
1015474252