A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes
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Complexity of type 2 diabetes mellitus data sets emerging from nutrigenomic research: a case for dimensionality reduction?PGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseMultiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twinsThe estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesisEvidence of an association between genetic variation of the coactivator PGC-1beta and obesityCoordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosisCandidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin actionParkinson's disease, insulin resistance and novel agents of neuroprotectionNew insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyondNetwork-based analysis of affected biological processes in type 2 diabetes modelsNovel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db miceAssociation between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD).The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in menAssociation and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic functionSkeletal Muscle Nucleo-Mitochondrial Crosstalk in Obesity and Type 2 Diabetes.The Association between Pediatric NAFLD and Common Genetic Variants.Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's diseaseCommon variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention ProgramTesting the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in TongansExercise, but not quercetin, ameliorates inflammation, mitochondrial biogenesis, and lipid metabolism in skeletal muscle after strenuous exercise by high-fat diet miceGenetic determinants of hepatic steatosis in man.The single nucleotide polymorphism Gly482Ser in the PGC-1α gene impairs exercise-induced slow-twitch muscle fibre transformation in humansGenetic Associations of PPARGC1A with Type 2 Diabetes: Differences among Populations with African Origins.Polymorphisms of the peroxisome proliferator-activated receptor-γ (rs1801282) and its coactivator-1 (rs8192673) are associated with obesity indexes in subjects with type 2 diabetes mellitus.Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditureGenetics of type 2 diabetes mellitus: status and perspectives.Genetics of Type 2 diabetes.PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study.Role of mitochondria in non-alcoholic fatty liver disease.Targeting PGC-1 alpha to control energy homeostasis.The genetics of gestational diabetes mellitus: evidence for relationship with type 2 diabetes mellitus.The role of the PGC1α Gly482Ser polymorphism in weight gain due to intensive diabetes therapy.PGC-1alpha in aging and anti-aging interventions.Magnolia extract (BL153) ameliorates kidney damage in a high fat diet-induced obesity mouse modelPGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.Genetic models of PGC-1 and glucose metabolism and homeostasisHepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells.Interaction effect of PGC-1α rs10517030 variants and energy intake in the risk of type 2 diabetes in middle-aged adults.Analysis of single nucleotide polymorphisms implicate mTOR signalling in the development of new-onset diabetes after transplantation.
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P2860
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A genetic variation in the PGC ...... eptibility to Type II diabetes
@ast
A genetic variation in the PGC ...... eptibility to Type II diabetes
@en
A genetic variation in the PGC ...... eptibility to Type II diabetes
@nl
type
label
A genetic variation in the PGC ...... eptibility to Type II diabetes
@ast
A genetic variation in the PGC ...... eptibility to Type II diabetes
@en
A genetic variation in the PGC ...... eptibility to Type II diabetes
@nl
prefLabel
A genetic variation in the PGC ...... eptibility to Type II diabetes
@ast
A genetic variation in the PGC ...... eptibility to Type II diabetes
@en
A genetic variation in the PGC ...... eptibility to Type II diabetes
@nl
P2093
P1433
P1476
A genetic variation in the PGC ...... eptibility to Type II diabetes
@en
P2093
H Kadowaki
T Kadowaki
P2888
P356
10.1007/S00125-002-0803-Z
P407
P577
2002-05-01T00:00:00Z
P5875
P6179
1052548600