The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding
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SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta productionSORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processesNeuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β productionCharacterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cellsFurin at the cutting edge: from protein traffic to embryogenesis and diseaseAnalysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during developmentRisk factor SORL1: from genetic association to functional validation in Alzheimer's diseaseMannose 6-phosphate receptors: new twists in the taleThe lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartmentsLoss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's diseaseMint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Functional organization of the sortilin Vps10p domain.SorCS3 does not require propeptide cleavage to bind nerve growth factor.Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing.A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes.Bacterial expression, purification, and model membrane reconstitution of the transmembrane and cytoplasmic domains of the human APP binding protein LR11/SorLA for NMR studies.Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome.LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease.GGA3 Interacts with a G Protein-Coupled Receptor and Modulates Its Cell Surface Export.A role for cargo in Arf-dependent adaptor recruitmentYeast Golgi-localized, gamma-Ear-containing, ADP-ribosylation factor-binding proteins are but adaptor protein-1 is not required for cell-free transport of membrane proteins from the trans-Golgi network to the prevacuolar compartment.Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention.LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease.Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid.Regulation of α2B-Adrenergic Receptor Cell Surface Transport by GGA1 and GGA2Toward a model for Arf GTPases as regulators of traffic at the Golgi.Sortilin and SorLA regulate neuronal sorting of trophic and dementia-linked proteins.N-linked oligosaccharides on the low density lipoprotein receptor homolog SorLA/LR11 are modified with terminal GalNAc-4-SO4 in kidney and brain.The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion.RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.Sorting receptor SORLA: cellular mechanisms and implications for disease.Functional Roles of the Interaction of APP and Lipoprotein Receptors.Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover.Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells.
P2860
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P2860
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding
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2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@ast
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@en
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@nl
type
label
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@ast
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@en
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@nl
prefLabel
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@ast
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@en
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@nl
P2093
P2860
P3181
P1433
P1476
The sorLA cytoplasmic domain i ...... m requirements for GGA binding
@en
P2093
August B Smit
Claus M Petersen
Jørgen Gliemann
Linda Jacobsen
Morten S Nielsen
Peder Madsen
Wijnand P M Geraerts
P2860
P3181
P356
10.1016/S0014-5793(01)03299-9
P407
P577
2002-01-30T00:00:00Z