Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia
about
Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemiaGAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow nicheDiscovery of Mer kinase inhibitors by virtual screening using Structural Protein-Ligand Interaction Fingerprints.Discovering Molecules That Regulate Efferocytosis Using Primary Human Macrophages and High Content ImagingStructural insights into the inhibited states of the Mer receptor tyrosine kinaseDiscovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic LeukemiaPseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase InhibitorsMERTK receptor tyrosine kinase is a therapeutic target in melanoma.UNC1062, a new and potent Mer inhibitor.Immunobiology of the TAM receptors.Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migrationTAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system.Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemiaUNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus.Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancerTAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.Gene expression profiles in BCL11B-siRNA treated malignant T cells.Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.Hollow core photonic crystal fiber for monitoring leukemia cells using surface enhanced Raman scattering (SERS)The AXL Receptor is a Sensor of Ligand Spatial HeterogeneityTaking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors.Targeting paediatric acute lymphoblastic leukaemia: novel therapies currently in developmentStructure-Based Virtual Screening of Commercially Available Compound Libraries.TAM receptors in leukemia: expression, signaling, and therapeutic implications.Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokersSynthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitorsMerTK inhibition in tumor leukocytes decreases tumor growth and metastasisEnhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines.Mer receptor tyrosine kinase is a therapeutic target in pre-B-cell acute lymphoblastic leukemia.Differential gene expression profiles of PPP2R5C-siRNA-treated malignant T cells.Biology of the TAM receptors.UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivoAberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia.Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.Pediatric relapsed or refractory leukemia: new pharmacotherapeutic developments and future directions.A novel aptamer-based competition strategy for ultrasensitive electrochemical detection of leukemia cells.Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status.
P2860
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P2860
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@ast
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@en
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@nl
type
label
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@ast
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@en
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@nl
prefLabel
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@ast
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@en
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@nl
P2093
P1476
Ectopic expression of the prot ...... l acute lymphoblastic leukemia
@en
P2093
Adil A Anwar
Amy K Keating
Dana B Salzberg
Douglas K Graham
Glenn K Matsushima
H Ralph Snodgrass
H Shelton Earp
Joanne Kurtzberg
Mark A Lovell
Michael J Schell
P304
P356
10.1158/1078-0432.CCR-05-2208
P407
P577
2006-05-01T00:00:00Z