Myofilament incorporation determines the stoichiometry of troponin I in transgenic expression and the rescue of a null mutation
about
Gene regulation, alternative splicing, and posttranslational modification of troponin subunits in cardiac development and adaptation: a focused reviewCell biology of sarcomeric protein engineering: disease modeling and therapeutic potentialMaturation status of sarcomere structure and function in human iPSC-derived cardiac myocytesCalcium-regulated conformational change in the C-terminal end segment of troponin I and its binding to tropomyosinThe heart-specific NH2-terminal extension regulates the molecular conformation and function of cardiac troponin IDeletion of a genomic segment containing the cardiac troponin I gene knocks down expression of the slow troponin T gene and impairs fatigue tolerance of diaphragm muscleTroponin T isoforms and posttranscriptional modifications: Evolution, regulation and functionMuscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switchingThin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts.Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathyMolecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residuesGenotype-specific pathogenic effects in human dilated cardiomyopathy.Coexistence of cardiac troponin T variants reduces heart efficiency.A dominantly negative mutation in cardiac troponin I at the interface with troponin T causes early remodeling in ventricular cardiomyocytesMutual rescues between two dominant negative mutations in cardiac troponin I and cardiac troponin TNH2-terminal truncations of cardiac troponin I and cardiac troponin T produce distinct effects on contractility and calcium homeostasis in adult cardiomyocytesInsights into restrictive cardiomyopathy from clinical and animal studies.Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary miceEffect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils.TNNT1, TNNT2, and TNNT3: Isoform genes, regulation, and structure-function relationships.Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I.
P2860
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P2860
Myofilament incorporation determines the stoichiometry of troponin I in transgenic expression and the rescue of a null mutation
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Myofilament incorporation dete ...... the rescue of a null mutation
@ast
Myofilament incorporation dete ...... the rescue of a null mutation
@en
Myofilament incorporation dete ...... the rescue of a null mutation
@nl
type
label
Myofilament incorporation dete ...... the rescue of a null mutation
@ast
Myofilament incorporation dete ...... the rescue of a null mutation
@en
Myofilament incorporation dete ...... the rescue of a null mutation
@nl
prefLabel
Myofilament incorporation dete ...... the rescue of a null mutation
@ast
Myofilament incorporation dete ...... the rescue of a null mutation
@en
Myofilament incorporation dete ...... the rescue of a null mutation
@nl
P2093
P2860
P1476
Myofilament incorporation dete ...... the rescue of a null mutation
@en
P2093
Han-Zhong Feng
M Moazzem Hossain
Xu-Pei Huang
P2860
P356
10.1016/J.ABB.2009.05.001
P407
P577
2009-07-01T00:00:00Z