UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells
about
Beyond T and DHT - novel steroid derivatives capable of wild type androgen receptor activationUnique patterns of molecular profiling between human prostate cancer LNCaP and PC-3 cellsUdp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancerA genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulationIntegration of the transcriptome and glycome for identification of glycan cell signatures.Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride.Investigation of the In Vitro and In Vivo efficiency of RM-532-105, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, in LAPC-4 prostate cancer cell and tumor modelsXenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family.Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism.Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosisRegulation of UGT2B Expression and Activity by miR-216b-5p in Liver Cancer Cell Lines.Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential.Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors.Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Steroid hormone synthetic pathways in prostate cancer.Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer.Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression.Characterisations of human prostate stem cells reveal deficiency in class I UGT enzymes as a novel mechanism for castration-resistant prostate cancer.Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels.Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression.Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression.Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential.ACSL3 promotes intratumoral steroidogenesis in prostate cancer cells.Stromal TGF-β signaling induces AR activation in prostate cancer.Increased severity of acute graft versus host disease as a result of differential expression following a homozygous gene deletion.Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry.The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors.Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys.Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance.
P2860
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P2860
UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@ast
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@en
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@nl
type
label
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@ast
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@en
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@nl
prefLabel
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@ast
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@en
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@nl
P2093
P2860
P356
P1476
UDP-glucuronosyltransferase 2B ...... in prostate cancer LNCaP cells
@en
P2093
Alain Bélanger
Olivier Barbier
Sarah Chouinard
P2860
P304
P356
10.1074/JBC.M703370200
P407
P577
2007-11-16T00:00:00Z