The ubiquitin ligase COP1 is a critical negative regulator of p53
about
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53Identification and characterization of the novel protein CCDC106 that interacts with p53 and promotes its degradationCUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasomeNuclear export regulation of COP1 by 14-3-3σ in response to DNA damageUSP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σPhosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53Acetylation is indispensable for p53 activationFBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activityp53 Stabilization and accumulation induced by human vaccinia-related kinase 1Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domainsA novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stabilityAutoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migrationNegative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunitCARPs are ubiquitin ligases that promote MDM2-independent p53 and phospho-p53ser20 degradationRNF38 encodes a nuclear ubiquitin protein ligase that modifies p53Molecular basis of Pirh2-mediated p53 ubiquitylationE3 ubiquitin ligase COP1 regulates the stability and functions of MTA1Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivationDifferential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosisp53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loopRegulation of p53 localization and transcription by the HECT domain E3 ligase WWP1Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationPLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2Induction of cullin 7 by DNA damage attenuates p53 functionNovel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1The role of tumor suppressor p53 in the antioxidant defense and metabolismProtein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitorNADPH oxidases: key modulators in aging and age-related cardiovascular diseases?Emerging Non-Canonical Functions and Regulation by p53: p53 and StemnessFunction and regulation of cullin-RING ubiquitin ligasesPathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Multiple functions of Jab1 are required for early embryonic development and growth potential in mice
P2860
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P2860
The ubiquitin ligase COP1 is a critical negative regulator of p53
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The ubiquitin ligase COP1 is a critical negative regulator of p53
@ast
The ubiquitin ligase COP1 is a critical negative regulator of p53
@en
The ubiquitin ligase COP1 is a critical negative regulator of p53
@nl
type
label
The ubiquitin ligase COP1 is a critical negative regulator of p53
@ast
The ubiquitin ligase COP1 is a critical negative regulator of p53
@en
The ubiquitin ligase COP1 is a critical negative regulator of p53
@nl
prefLabel
The ubiquitin ligase COP1 is a critical negative regulator of p53
@ast
The ubiquitin ligase COP1 is a critical negative regulator of p53
@en
The ubiquitin ligase COP1 is a critical negative regulator of p53
@nl
P2093
P3181
P356
P1433
P1476
The ubiquitin ligase COP1 is a critical negative regulator of p53
@en
P2093
David Arnott
Gretchen D Frantz
Hartmut Koeppen
Harumi Shimizu
Ingrid Wertz
Karen O'Rourke
Patrick Dowd
Vishva M Dixit
P2888
P3181
P356
10.1038/NATURE02514
P407
P50
P577
2004-05-06T00:00:00Z
P6179
1030067716