The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1 - Wikidata - thesis-toulmin - TriplyDB

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1

http://www.wikidata.org/entity/Q28258178

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The transcription factor p53: not a repressor, solely an activator Human papillomavirus-16 E7 interacts with Siva-1 and modulates apoptosis in HaCaT human immortalized keratinocytes The inflammatory and normal transcriptome of mouse bladder detrusor and mucosa E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Components of the antigen processing and presentation pathway revealed by gene expression microarray analysis following B cell antigen receptor (BCR) stimulation Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth Suppression of p53 activity by Siva1 E2F1 localizes predominantly to neuronal cytoplasm and fails to induce expression of its transcriptional targets in human immunodeficiency virus-induced neuronal damage.A retinoblastoma orthologue is a major regulator of S-phase, mitotic, and developmental gene expression in Dictyostelium Siva-1 promotes K-48 polyubiquitination of TRAF2 and inhibits TCR-mediated activation of NF-kappaB.Two Faces of SIVA.The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development Differential Gene Expression Patterns in Chicken Cardiomyocytes during Hydrogen Peroxide-Induced Apoptosis The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival.Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.Life and death decisions by the E2F transcription factors.Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation.E2F1 death pathways as targets for cancer therapy Multifaceted functions of Siva-1: more than an Indian God of Destruction Regulation of the LPA2 receptor signaling through the carboxyl-terminal tail-mediated protein-protein interactions Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells.SLIMMER (FHL1B/KyoT3) interacts with the proapoptotic protein Siva-1 (CD27BP) and delays skeletal myoblast apoptosis.Egr-1 upregulates Siva-1 expression and induces cardiac fibroblast apoptosis.Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase.Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate.(Z)-1,1-Dichloro-2-(4-methoxyphenyl)-3-phenylcyclopropane induces concentration-dependent growth inhibition, apoptosis, and coordinates regulation of apoptotic genes in TRAMP cells.Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis.Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism.The p53-induced Siva-1 plays a significant role in cisplatin-mediated apoptosis.PERP, a p53 proapoptotic target, mediates apoptotic cell death in renal ischemia.Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death.Identification of apoptosis-related genes and transcription variations in response to microcystin-LR in zebrafish liver.Notch signaling and neuronal death in stroke.Siva-1 emerges as a tissue-specific oncogene beyond its classic role of a proapoptotic gene

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P2860

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1

http://www.wikidata.org/entity/Q28258178

description

2004 nî lūn-bûn

@nan

2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2004年の論文

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2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

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2004年论文

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name

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@ast

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@en

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@nl

type

label

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@ast

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@en

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@nl

prefLabel

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@ast

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@en

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@nl

P1433

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P1476

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P2860

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P698

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P356

P1433

Journal of Biological Chemistry

P1476

The proapoptotic gene SIVA is ...... tumor suppressors p53 and E2F1

@en

P2093

Andre Fortin

http://www.w3.org/2001/XMLSchema#string

David S Park

http://www.w3.org/2001/XMLSchema#string

Jason G MacLaurin

http://www.w3.org/2001/XMLSchema#string

Neena Kushwaha

http://www.w3.org/2001/XMLSchema#string

Nicole Arbour

http://www.w3.org/2001/XMLSchema#string

Ruth S Slack

http://www.w3.org/2001/XMLSchema#string

Sean P Cregan

http://www.w3.org/2001/XMLSchema#string

Steven M Callaghan

http://www.w3.org/2001/XMLSchema#string

P2860

Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis

p53 has a direct apoptogenic role at the mitochondria

CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein

Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway

p53, the cellular gatekeeper for growth and division

The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat

Perp is a mediator of p53-dependent apoptosis in diverse cell types

P304

28706-14

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

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10.1074/JBC.M400376200

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P433

27

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P478

279

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P577

2004-07-02T00:00:00Z

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P698

15105421

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