Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system - Wikidata - thesis-toulmin - TriplyDB

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

http://www.wikidata.org/entity/Q28258706

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Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels Altered ribostasis: RNA-protein granules in degenerative disorders Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death Targeting p97 to Disrupt Protein Homeostasis in Cancer The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS The Mcm2-7 replicative helicase: a promising chemotherapeutic target From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation Cardiac-Restricted Expression of VCP/TER94 RNAi or Disease Alleles Perturbs Drosophila Heart Structure and Impairs Function.Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP)Molecular Basis and Regulation of OTULIN-LUBAC Interaction Peeling away the layers of ubiquitin signaling complexities with synthetic ubiquitin-protein conjugates.Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2 Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products.New Regulators of Clathrin-Mediated Endocytosis Identified in Saccharomyces cerevisiae by Systematic Quantitative Fluorescence Microscopy.Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane The budding yeast Cdc48(Shp1) complex promotes cell cycle progression by positive regulation of protein phosphatase 1 (Glc7).The Cdc48 protein and its cofactor Vms1 are involved in Cdc13 protein degradation.Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97.Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome.UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer The Cilium: Cellular Antenna and Central Processing Unit Varicella-Zoster Virus Infectious Cycle: ER Stress, Autophagic Flux, and Amphisome-Mediated Trafficking Mutations in the Human AAA+ Chaperone p97 and Related Diseases XPC: Going where no DNA damage sensor has gone before Ubiquitylation, neddylation and the DNA damage response Torsins: not your typical AAA+ ATPases A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease Cleaning up in the endoplasmic reticulum: ubiquitin in charge

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Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

http://www.wikidata.org/entity/Q28258706

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@ast

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@en

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@nl

type

label

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@ast

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@en

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@nl

prefLabel

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@ast

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@en

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@nl

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P1433

Nature Cell Biology

P1476

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

@en

P2093

Monika Bug

http://www.w3.org/2001/XMLSchema#string

Sebastian Bremer

http://www.w3.org/2001/XMLSchema#string

P2860

VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

Chromosome alignment and segregation regulated by ubiquitination of survivin

Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

Imbalances in p97 co-factor interactions in human proteinopathy

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

Defining the human deubiquitinating enzyme interaction landscape

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117-23

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scholarly article

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849552

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10.1038/NCB2407

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2

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14

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2012-02-02T00:00:00Z

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221799036

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1009717651

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22298039

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