Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
about
TRP channels in neurogastroenterology: opportunities for therapeutic interventionTransient receptor potential (TRP) channels as drug targets for diseases of the digestive systemThe Effect of Capsaicin on Salivary Gland DysfunctionRecent additions in the treatment of coughFunctionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational dataCPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate ThermosensationNociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain PathologiesTransient activation of specific neurons in mice by selective expression of the capsaicin receptor.Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease.Increased susceptibility to cardiovascular effects of dihydrocapcaicin in resuscitated rats. Cardiovascular effects of dihydrocapsaicinDrug-induced mild therapeutic hypothermia obtained by administration of a transient receptor potential vanilloid type 1 agonist.Molecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons.Capsaicin inhibits the spontaneous pacemaker activity in interstitial cells of cajal from the small intestine of mouse.Endocannabinoid-dependent LTD in a nociceptive synapse requires activation of a presynaptic TRPV-like receptor.New insights into the pharmacology of the bladderDisruption of the transient receptor potential vanilloid 1 can affect survival, bacterial clearance, and cytokine gene expression during murine sepsis.Intracellular long-chain acyl CoAs activate TRPV1 channelsDeveloping piperine towards TRPV1 and GABAA receptor ligands--synthesis of piperine analogs via Heck-coupling of conjugated dienes.A combined coarse-grained and all-atom simulation of TRPV1 channel gating and heat activationMice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophyCytomegalovirus Infection Triggers the Secretion of the PPARγ Agonists 15-Hydroxyeicosatetraenoic Acid (15-HETE) and 13-Hydroxyoctadecadienoic Acid (13-HODE) in Human Cytotrophoblasts and Placental Cultures.Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1Constrained TRPV1 agonists synthesized via silver-mediated intramolecular azo-methine ylide cycloaddition of α-iminoamides.Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat.Gut pain & visceral hypersensitivityIntracellular proton-mediated activation of TRPV3 channels accounts for the exfoliation effect of α-hydroxyl acids on keratinocytes.Capsaicin mediates caspases activation and induces apoptosis through P38 and JNK MAPK pathways in human renal carcinomaAlteration in TRPV1 and Muscarinic (M3) receptor expression and function in idiopathic overactive bladder urothelial cells.TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson's disease via CNTF.The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensorDiabetes Stimulates Osteoclastogenesis by Acidosis-Induced Activation of Transient Receptor Potential Cation Channels.TRPV1: a new target for treatment of visceral pain in IBS?Role of TRPV1 in inflammation-induced airway hypersensitivityIdentifying biological markers of activity in human nociceptive pathways to facilitate analgesic drug development.TRPV1 channel-mediated bilateral allodynia induced by unilateral masseter muscle inflammation in ratsKunitz-Type Peptide HCRG21 from the Sea Anemone Heteractis crispa Is a Full Antagonist of the TRPV1 Receptor.Visceral pain hypersensitivity in functional gastrointestinal disorders.Use of sensory methods for detecting target engagement in clinical trials of new analgesics.Transient receptor potential vanilloid-1 antagonists: a survey of recent patent literature.Effect of capsaicin on prostate cancer cells.
P2860
Q24618774-E7476E67-4A99-40C2-865E-B0C86E5E9B24Q24627020-A6713C4C-5F32-45AA-BE04-F69E63F669F9Q26747031-35BC56EF-C831-4D54-B21A-0DEFC32304FBQ26861326-421C7B27-B3BC-40DE-BC25-C371642F2887Q26865131-4C5CAFC8-E004-4720-915F-69E6BB6EF4E8Q27323262-A4B2CE65-211D-4216-A3BE-A88CD40D951FQ28073883-AAB3BD2F-904F-42D5-AFE5-84332DFFCB3EQ30537339-F3C1D170-2BD0-452D-AD0A-AC7DE7FA221FQ30844366-0C657285-38E2-4DB8-958D-A572C720F1C1Q33679466-798DE6AE-6725-41F4-8164-3A906DE6766BQ33713377-FB55A22A-A067-4969-8E70-A475F71D2EC1Q33755790-07AD3CF7-2AF5-452B-AE9D-69E3F5D4AC10Q34028417-0049D1F1-C56D-461C-963A-C3591F8DBED1Q34379705-96F8D2CC-36EF-44F3-B55E-60D5E25B5B63Q34931019-93C2DE94-6EFE-4FF3-AFEC-722C3873C606Q35057332-5105C15C-7CF9-4F37-B8F7-6FACAEDB9FD0Q35163419-ACE89121-31C8-44DD-BB9D-5C393C57AF06Q35463986-9013BFE6-F6D4-49C6-BF52-31F178511DE6Q35543125-76CCBEEB-C741-4E83-9C03-E040E75F989EQ35577699-EF547A06-678F-4317-8B78-DF622AE94CA9Q35690401-A14C6AB8-BBBA-424F-8E40-43B0AE33501EQ36025357-B242F952-1B70-46D2-8331-FE90CE046DD0Q36057551-A7A272B3-106A-4630-BDBD-5FEB0F0E2EA7Q36083250-CC50CEEE-0392-4E75-A558-467DC957C6C8Q36110577-D1BBBCDE-675B-41AF-A503-8D4147BBAA0DQ36122117-DC7EA8BF-9F52-474A-B8CD-5BE724425C20Q36160833-75A17181-9ED9-40B7-9B84-3068977B34F4Q36388886-F47FC7B3-9A7C-455E-8FB1-9C943644AAE8Q36824652-0B59773F-DD85-40CD-903C-A33325E10262Q37023861-1AE37153-14B2-4298-A0EF-46F100DD2E9CQ37137204-491C4C3F-544C-4F7F-BB67-2F6809622BA2Q37193228-BD3D50C3-1817-4ADE-9B8B-599A9D14BFF8Q37246141-2DFBFDD5-49DE-4B57-A46F-F6D1C64D2317Q37308100-5E8F95C3-124D-4922-A3CC-3DA991339D92Q37432051-5A6F2A7A-C8C0-4FBC-B688-316D3447A40FQ37539438-ED8A58F9-DB62-41FD-8222-7A3F2F829B7DQ37557017-97B28378-3377-420F-9674-006C9E6BFA0CQ37605357-88D2A99D-0D16-48AF-B268-D569B7570A37Q37768452-47339B80-BC66-4409-96E2-3890C1FC27DBQ37808217-13CC45D2-6977-4D81-B89A-09B45298156B
P2860
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@ast
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@en
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@nl
type
label
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@ast
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@en
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@nl
prefLabel
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@ast
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@en
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@nl
P3181
P1476
Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms
@en
P2093
Arpad Szallasi
Martin J Gunthorpe
P3181
P356
10.2174/138161208783330754
P407
P577
2008-01-01T00:00:00Z