IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis - Wikidata - thesis-toulmin - TriplyDB

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

http://www.wikidata.org/entity/Q28268370

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Genetics of psoriasis and pharmacogenetics of biological drugs Brodalumab for the Treatment of Psoriasis: A Review of Phase III Trials Ixekizumab for the Treatment of Psoriasis: A Review of Phase III Trials Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease Immunology of psoriasis New era of biologic therapeutics in atopic dermatitis Targeting of interleukin-17 in the treatment of psoriasis Putting together the psoriasis puzzle: an update on developing targeted therapies Interleukin-17 inhibitors. A new era in treatment of psoriasis and other skin diseases Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm.Early tissue responses in psoriasis to the antitumour necrosis factor-α biologic etanercept suggest reduced interleukin-17 receptor expression and signalling.Etiology of leukocyte adhesion deficiency-associated periodontitis revisited: not a raging infection but a raging inflammatory response.An epidemiological study on trigger factors and quality of life in psoriatic patients IL-17/Th17 pathway is activated in acne lesions Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease IL-17 in severe asthma. Where do we stand?Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.Suppression of molecular inflammatory pathways by Toll-like receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation.Antioxidant and anti-inflammatory activity of Ocimum labiatum extract and isolated labdane diterpenoid.IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model CARD14 expression in dermal endothelial cells in psoriasis.Effect of interleukin-17 on receptor-interacting protein 4 expression and keratinocyte proliferation.Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways Update on psoriasis immunopathogenesis and targeted immunotherapy.The role of IL-17 in vitiligo: A review Potential role of ixekizumab in the treatment of moderate-to-severe plaque psoriasis Signaling through purinergic receptors for ATP induces human cutaneous innate and adaptive Th17 responses: implications in the pathogenesis of psoriasis TREM-1 as a potential therapeutic target in psoriasis The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.Updates on Psoriasis and Cutaneous Oncology: Proceedings from the 2013 MauiDerm Meeting.Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function.Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study.Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.The Th17 pathway as a therapeutic target in rheumatoid arthritis and other autoimmune and inflammatory disorders.Keratin 17: a critical player in the pathogenesis of psoriasis.IL-17 targeted therapies for psoriasis.Interleukin-17A: a unique pathway in immune-mediated diseases: psoriasis, psoriatic arthritis and rheumatoid arthritis.Inhibition of IL-17 as a pharmacological approach for IBD.The mechanistic basis for psoriasis immunopathogenesis: translating genotype to phenotype. Report of a workshop, Venice, 2012.

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P2860

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

http://www.wikidata.org/entity/Q28268370

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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IL-17A is essential for cell a ...... its in subjects with psoriasis

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IL-17A is essential for cell a ...... its in subjects with psoriasis

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IL-17A is essential for cell a ...... its in subjects with psoriasis

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J.JACI.2012.04.024

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The Journal of Allergy and Clinical Immunology

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IL-17A is essential for cell a ...... its in subjects with psoriasis

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Artemis Katcherian

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Gregory S Cameron

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Inna Cueto

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James G Krueger

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Juliet McColm

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Krista M Phipps

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Mayte Suárez-Fariñas

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Patrick A Haslett

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Robert W Hoffman

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Scott Fretzin

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P2860

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Circulating Th17, Th22, and Th1 cells are increased in psoriasis

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

"Harshlighting" small blemishes on microarrays.

IL-22 increases the innate immunity of tissues

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis

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