Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene - Wikidata - thesis-toulmin - TriplyDB

Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

http://www.wikidata.org/entity/Q28285297

about

The DNA sequence of the human X chromosome Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP)Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease Progress and problems in understanding and managing primary Epstein-Barr virus infections XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells The X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62dok (Dok1) and activates NF-kappa B Siglecs in the immune system The molecular pathology of primary immunodeficiencies Responses to Microbial Challenges by SLAMF Receptors Severe infectious diseases of childhood as monogenic inborn errors of immunity Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis Hemophagocytic lymphohistiocytosis: an update on diagnosis and pathogenesis X-linked lymphoproliferative syndromes: brothers or distant cousins?NK Cell Influence on the Outcome of Primary Epstein-Barr Virus Infection The Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) Protein The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2)Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product Interaction domains: from simple binding events to complex cellular behavior Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors A spectrum of mutations in SH2D1A that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnesses Association of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinase Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)Macrophage activation syndrome: advances towards understanding pathogenesis CS1 (SLAMF7) inhibits production of proinflammatory cytokines by activated monocytes Association between SAP and FynT: Inducible SH3 domain-mediated interaction controlled by engagement of the SLAM receptor Impaired immune responses and prolonged allograft survival in Sly1 mutant mice Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor The adaptor protein SAP directly associates with CD3ζ chain and regulates T cell receptor signaling.Genetic characterisation of spontaneous ankylosing arthropathy with unique inheritance from Fas-deficient strains of mice Expansion of murine gammaherpesvirus latently infected B cells requires T follicular help.Common variable immunodeficiency: etiological and treatment issues.SLAM-family receptors: immune regulators with or without SAP-family adaptors.

P2860

9c58ac3d6c1bf51de314ea628c936cc674e22d8f

P248

Q21735931-D842CA88-E07B-4E83-B93F-D4F5081C67E9 Q22010776-FC227678-AC4D-440C-A25D-BAA30DA9D1FB Q24291489-980C6DAD-E93E-4E9C-B2CE-717299405C65 Q24292245-9592F128-684F-4600-9FB7-030E22587B6D Q24297438-1208D1B5-F2C9-4D52-BAD2-E3A14BF609D4 Q24303904-B39D30C0-9DBF-41AE-9D72-00EA17DEA0EB Q24515076-10BF6695-FF7B-4C6E-A03D-0084823B2F14 Q24535874-ABA03AA5-AB53-4A20-AC12-A609C77481E5 Q24536218-8C5A68AF-6F42-4E7F-8E29-771A36932ECC Q24597706-730755C9-2A8E-4B06-82D8-08EE53B2AF67 Q24610800-27C22018-80EA-4C53-A592-F476A66DFD14 Q24675566-E1192547-8067-44EF-8E25-B0773DC30EE9 Q24676168-9877704A-C293-4605-9E33-1484054FA9E0 Q24681336-82BE25F9-61E0-426D-9A65-E661441FB414 Q24682458-063739BB-6ECA-4CFB-8E97-DFE26F14C5F1 Q24685932-08840D9F-251C-4BF7-A998-C4CC0E4BC876 Q26772707-ADB2FE1D-659C-4A81-97DD-0F9293ED9F16 Q26775891-C3238BA6-A548-46E2-BB53-CC1FC826060F Q26776499-63B75A4B-BF04-4B97-97B3-E56163BB4968 Q27023603-A6D3DEE3-E8E3-4628-8240-E4475C1A97E2 Q27690253-2F4882D5-1601-4DD0-A49C-A8639493FE72 Q28069456-9A9CFDAD-FFC7-4662-A371-142F72DB1DE6 Q28069519-50D840BD-BA70-402E-B993-B0454E6683BB Q28181256-82F6E383-44FA-4A8C-9F34-023976D9F540 Q28209604-6D9D375A-FF4D-4031-A4E9-A1EB988F4AC2 Q28209614-41FC2AC9-3AAB-4417-9CF6-C734F55D3EDD Q28216360-BCD8E563-4F2D-4560-867E-DD3AF6377DCC Q28216635-F048C2DB-A994-4C80-85F5-8A49D14FA8A4 Q28216840-88A79CFE-342C-4415-A374-ED27BD0694CD Q28271106-11E7A87D-478E-47CB-B15A-C6C87EEE635C Q28284000-3F6001DA-1C75-45B0-AA0C-F796F57F0F6C Q28291155-FF1D6D8C-3635-4900-BF9F-0D02A14A86C7 Q28585941-3D53A607-2338-4306-827F-2635426BFF41 Q28586424-F22D562F-FC16-4592-B906-00BBC5EA6ADD Q28593740-DBF5B4B5-4B47-4540-873C-76A5187B29DF Q30010025-4C81F7BC-C12B-41C0-9486-A2282445DAF0 Q33237878-95BA1864-F198-49A8-95EA-272E93FB775B Q33553789-A0DCA37F-18C9-44F6-914B-A7C1B16D2710 Q33621805-1B70C016-B457-408A-9B5B-F7410C6667C5 Q33693795-755B1E87-D72D-4056-A38C-D53D53716C61

P2860

Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

http://www.wikidata.org/entity/Q28285297

description

1998 nî lūn-bûn

@nan

1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Host response to EBV infection ...... in an SH2-domain encoding gene

@ast

Host response to EBV infection ...... in an SH2-domain encoding gene

@en

Host response to EBV infection ...... in an SH2-domain encoding gene

@nl

type

label

Host response to EBV infection ...... in an SH2-domain encoding gene

@ast

Host response to EBV infection ...... in an SH2-domain encoding gene

@en

Host response to EBV infection ...... in an SH2-domain encoding gene

@nl

prefLabel

Host response to EBV infection ...... in an SH2-domain encoding gene

@ast

Host response to EBV infection ...... in an SH2-domain encoding gene

@en

Host response to EBV infection ...... in an SH2-domain encoding gene

@nl

P1433

Q28285297-8A67A529-E296-4AFE-AA76-A537B6E3E4F8

P1476

Q28285297-8C068BD1-502E-4F8F-B0C0-059B5484A031

P2093

Q28285297-01F35AA9-F8A8-48D2-AB3E-2E4B4404CAD8

Q28285297-0338ADCD-18C0-41EB-A194-CA2A65C31FCB

Q28285297-0542D42E-94AD-4C30-B8C3-66A9B2B4990B

Q28285297-08814C14-A227-45DD-9B53-47B6804957FF

Q28285297-19356B61-871B-48EB-9BFC-ED44D4FD0C34

Q28285297-254F4680-D4DC-4283-A21A-DB209545F7F5

Q28285297-25D80928-F098-4F5B-9B21-1C6EA357B78C

Q28285297-27B57FE2-3B2C-4208-81DD-C73980888DB4

Q28285297-32B0B356-93F2-47FC-A1FA-47D736C78AFA

Q28285297-34F577B4-003E-45C1-917B-60597EE30277

P2888

Q28285297-9F999C18-AE60-450C-A1BA-3BDE6BCDB3AE

P304

Q28285297-064C7EC4-0FE2-4060-9B2D-397A26049ED6

P31

Q28285297-651459EC-06BE-44A9-8CC3-9D89F95A01C8

P3181

Q28285297-E391090C-71B0-460E-9D50-88A11B3D15AF

P356

Q28285297-1C33F906-2BCE-428D-BFEF-13EFB7AED1FD

P407

Q28285297-2D8CC7B6-98BC-4F50-A92C-139C47BAEEF0

P433

Q28285297-CE50581E-108B-4204-9282-2CFF5EBA76E5

P478

Q28285297-6F55122A-E6D3-4AE9-BA5A-0668034F12A1

P50

Q28285297-164018BB-EB14-4479-BE67-5E9F4C3DF219

Q28285297-5AFAD315-1835-4C6E-862F-1457ABD3192D

Q28285297-5BC67E6C-9462-49D7-B67F-2B4C34FE9AC0

Q28285297-7AF23835-35D7-4791-A8DA-7E9CA3534EF9

P577

Q28285297-C4AABC1B-96C4-4323-9259-ADA290D1EE47

P6179

Q28285297-94AB2BCE-9BEC-43DB-BD54-500E473E1DAF

P698

Q28285297-8769174A-BEC1-43A9-9629-83C6A97ACB1E

P3181

P356

P1433

Nature Genetics

P1476

Host response to EBV infection ...... in an SH2-domain encoding gene

@en

P2093

A Dunham

http://www.w3.org/2001/XMLSchema#string

A Harris

http://www.w3.org/2001/XMLSchema#string

A J Coffey

http://www.w3.org/2001/XMLSchema#string

A Jones

http://www.w3.org/2001/XMLSchema#string

A Lanyi

http://www.w3.org/2001/XMLSchema#string

A P Cahn

http://www.w3.org/2001/XMLSchema#string

B H Behloradsky

http://www.w3.org/2001/XMLSchema#string

B Sylla

http://www.w3.org/2001/XMLSchema#string

C J Shaw-Smith

http://www.w3.org/2001/XMLSchema#string

D R Bentley

http://www.w3.org/2001/XMLSchema#string

P2888

P304

129-35

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1381864

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/2424

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P50

Brunella Franco

Alessandra Bolino

P577

1998-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1022544887

http://www.w3.org/2001/XMLSchema#string

P698

9771704

http://www.w3.org/2001/XMLSchema#string