The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo
about
GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high dosesThe conditioned medium from a stable human GDF3-expressing CHO cell line, induces the differentiation of PC12 cellsGrowth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migrationNodal morphogensGrowth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesityCripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturationGrowth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axisMultiple signaling pathways coordinate to induce a threshold response in a chordate embryoRegulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signalingA continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells.The determination factors of left-right asymmetry disorders- a short review.Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryoTranscription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.Activin/Nodal signalling before implantation: setting the stage for embryo patterning.Embryonic mesoderm and endoderm induction requires the actions of non-embryonic Nodal-related ligands and Mxtx2A comprehensive survey of copy number variation in 18 diverse pig populations and identification of candidate copy number variable genes associated with complex traits.Growth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis.The hypoblast (visceral endoderm): an evo-devo perspective.Molecular basis of Mammalian embryonic stem cell pluripotency and self-renewal.Emerging roles for the transforming growth factor-{beta} superfamily in regulating adiposity and energy expenditureCripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.Mesoderm induction: from caps to chips.Regulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cellsCripto/GRP78 modulation of the TGF-β pathway in development and oncogenesisDeficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose.Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo.Activin signaling: effects on body composition and mitochondrial energy metabolismFrom embryonic development to human diseases: The functional role of caveolae/caveolin.An evolving web of signaling networks regulated by Cripto-1.The transcription factor Pitx2 positions the embryonic axis and regulates twinning.Plasticity underlies tumor progression: role of Nodal signaling.TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.Activins and Inhibins: Roles in Development, Physiology, and Disease.Agonists and Antagonists of TGF-β Family Ligands.Structural Biology and Evolution of the TGF-β FamilyEstablishment of the Vertebrate Germ Layers.GDF3 inhibits the growth of breast cancer cells and promotes the apoptosis induced by Taxol.An embryo-specific expressing TGF-β family protein, growth-differentiation factor 3 (GDF3), augments progression of B16 melanoma.Niche-mediated control of human embryonic stem cell self-renewal and differentiation.The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling.
P2860
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P2860
The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2006 թվականի հունվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@ast
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@en
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@nl
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The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@ast
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@en
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@nl
prefLabel
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@ast
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@en
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
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P2093
P356
P1433
P1476
The Vg1-related protein Gdf3 a ...... pre-gastrulation mouse embryo
@en
P2093
Akira Sato
Canhe Chen
Chester W Brown
Dianne E Houston-Hawkins
Martin M Matzuk
Raymond Habas
Stephanie M Ware
P304
P356
10.1242/DEV.02210
P407
P577
2006-01-01T00:00:00Z