Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures - Wikidata - thesis-toulmin - TriplyDB

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

http://www.wikidata.org/entity/Q28299915

about

What does our genome encode?Targeting DNA With Fingers and TALENs Precision editing of large animal genomes Newer gene editing technologies toward HIV gene therapy Gene targeting, genome editing: from Dolly to editors Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Towards a new era in medicine: therapeutic genome editing Origins of Programmable Nucleases for Genome Engineering Single-Base Pair Genome Editing in Human Cells by Using Site-Specific Endonucleases From Gene Targeting to Genome Editing: Transgenic animals applications and beyond Enabling functional genomics with genome engineering Making designer mutants in model organisms Using genetic methods to define the targets of compounds with antimalarial activity Current translational and clinical practices in hematopoietic cell and gene therapy Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy Current and Emerging Therapies for the Treatment of Cystic Fibrosis or Mitigation of Its Symptoms Zebrafish as a disease model for studying human hepatocellular carcinoma Targeted genome editing across species using ZFNs and TALENs Mutants of Cre recombinase with improved accuracy Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)Stable gene targeting in human cells using single-strand oligonucleotides with modified bases Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification Genome Engineering With Zinc-Finger Nucleases Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering Genetic engineering of human pluripotent cells using TALE nucleases Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.Efficient methods for targeted mutagenesis in zebrafish using zinc-finger nucleases: data from targeting of nine genes using CompoZr or CoDA ZFNs.Engineering and Evolution of Saccharomyces cerevisiae to Produce Biofuels and Chemicals.Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing.High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity Targeted genome engineering techniques in Drosophila.Genome-Edited T Cell Therapies.Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection.Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.Selection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases.Methods for targeted mutagenesis in zebrafish using TALENs Mouse genome engineering using designer nucleases.

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Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

http://www.wikidata.org/entity/Q28299915

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

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Enhancing zinc-finger-nuclease ...... te heterodimeric architectures

@en

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Danny F Xia

http://www.w3.org/2001/XMLSchema#string

Fyodor D Urnov

http://www.w3.org/2001/XMLSchema#string

Jeffrey C Miller

http://www.w3.org/2001/XMLSchema#string

Jianbin Wang

http://www.w3.org/2001/XMLSchema#string

Matthew C Mendel

http://www.w3.org/2001/XMLSchema#string

Michael C Holmes

http://www.w3.org/2001/XMLSchema#string

Shon G Greenberg

http://www.w3.org/2001/XMLSchema#string

Thuy D Vo

http://www.w3.org/2001/XMLSchema#string

P2860

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

Knockout rats via embryo microinjection of zinc-finger nucleases

Progress and prospects: zinc-finger nucleases as gene therapy agents

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

FokI dimerization is required for DNA cleavage

Structure of FokI has implications for DNA cleavage

A rapid method for localized mutagenesis of yeast genes

Close-range electrostatic interactions in proteins

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

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74-9

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scholarly article

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929991

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10.1038/NMETH.1539

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1

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8

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Philip D Gregory

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2011-01-01T00:00:00Z

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49658677

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1010147854

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21131970

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