Role of mitogen-activated protein kinase kinase 4 in cancer - Wikidata - thesis-toulmin - TriplyDB

Role of mitogen-activated protein kinase kinase 4 in cancer

Role of mitogen-activated protein kinase kinase 4 in cancer

http://www.wikidata.org/entity/Q28301942

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miR-92a inhibits vascular smooth muscle cell apoptosis: role of the MKK4-JNK pathway The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer Id1 induces apoptosis through inhibition of RORgammat expression Role of JNK in a Trp53-dependent mouse model of breast cancer.Kinase modulation of androgen receptor signaling: implications for prostate cancer Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis.Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.ERK and JNK activation is essential for oncogenic transformation by v-Rel.Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways.The role of JNK in the development of hepatocellular carcinoma.Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling 7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4.Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.Protein kinases as switches for the function of upstream stimulatory factors: implications for tissue injury and cancer Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation.The soft underbelly of tumor cells.Role of JNK in mammary gland development and breast cancer.Genetic variation in the TNF/TRAF2/ASK1/p38 kinase signaling pathway as markers for postoperative pulmonary complications in lung cancer patients.Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.The association between -1304T>G polymorphism in the promoter of mitogen-activated protein kinase kinase 4 gene and the risk of cervical cancer in Chinese population Quercetin and Cisplatin combined treatment altered cell cycle and mitogen activated protein kinase expressions in malignant mesotelioma cells.Sexual dimorphism in periapical inflammation and bone loss from mitogen-activated protein kinase phosphatase-1 deficient mice JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila.Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.Co-opted JNK/SAPK signaling in Wnt/beta-catenin-induced tumorigenesis.Loss of Wip1 sensitizes cells to stress- and DNA damage-induced apoptosis.MEK4 function, genistein treatment, and invasion of human prostate cancer cells Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase.The role of mitogen- and stress-activated protein kinase pathways in melanoma.Building on the foundation of daring hypotheses: using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization.Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological and pathological processes to design novel therapeutic strategies.Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update.The 2 Faces of JNK Signaling in Cancer.Protective Mechanisms of Flavonoids in Parkinson's Disease.IFNs-signaling effects on lung cancer: an up-to-date pathways-specific review.Impact of polyphenolic components from mulberry on apoptosis of vascular smooth muscle cells.Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression.β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1.

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Role of mitogen-activated protein kinase kinase 4 in cancer

http://www.wikidata.org/entity/Q28301942

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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Role of mitogen-activated protein kinase kinase 4 in cancer

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A J Whitmarsh

http://www.w3.org/2001/XMLSchema#string

R J Davis

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P2860

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

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10.1038/SJ.ONC.1210410

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22

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26

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