Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants
about
Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degenerationA new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.Genetic regulation of pituitary gland development in human and mouseOTX5 regulates pineal expression of the zebrafish REV-ERB alpha through a new DNA binding site.Otx2 and Oct4 drive early enhancer activation during embryonic stem cell transition from naive pluripotency.Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma.OTX2 microphthalmia syndrome: four novel mutations and delineation of a phenotypeOtx2 ChIP-seq reveals unique and redundant functions in the mature mouse retinaTranscriptional regulation of neural retina leucine zipper (Nrl), a photoreceptor cell fate determinantEye development genes and known syndromesRegulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding siteATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreousOTX2 represses myogenic and neuronal differentiation in medulloblastoma cells.Regulation of photoreceptor gene expression by Crx-associated transcription factor networkA Simple Grammar Defines Activating and Repressing cis-Regulatory Elements in PhotoreceptorsA rare de novo nonsense mutation in OTX2 causes early onset retinal dystrophy and pituitary dysfunction.The molecular basis of hypopituitarismMolecular and Clinical Findings in Patients with LHX4 and OTX2 Mutations.Otx2 induction of the gonadotropin-releasing hormone promoter is modulated by direct interactions with Grg co-repressors.Quantitative fine-tuning of photoreceptor cis-regulatory elements through affinity modulation of transcription factor binding sites.Genome-Wide Target Analyses of Otx2 Homeoprotein in Postnatal CortexSeparable transcriptional regulatory domains within Otd control photoreceptor terminal differentiation events.CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors.Comprehensive interactome of Otx2 in the adult mouse neural retina.Agnathia-otocephaly complex and asymmetric velopharyngeal insufficiency due to an in-frame duplication in OTX2.
P2860
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P2860
Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@ast
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@en
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@nl
type
label
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@ast
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@en
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@nl
prefLabel
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@ast
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@en
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@nl
P2093
P2860
P1476
Molecular dissection reveals d ...... e effect in human OTX2 mutants
@en
P2093
Gilbert Brun
Gilles Chatelain
Nicolas Fossat
P2860
P2888
P304
P356
10.1007/S00109-006-0048-2
P407
P577
2006-04-11T00:00:00Z
P6179
1032265859