The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5
about
Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses.Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells.Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors.Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient.Investigational drugs for head and neck cancer.Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex.The proteasome deubiquitinase inhibitor b-AP15 enhances DR5 activation-induced apoptosis through stabilizing DR5.NVP-BKM120 inhibits colon cancer growth via FoxO3a-dependent PUMA induction.Hsp90 inhibitor sensitizes TRAIL-mediated apoptosis via chop-dependent DR5 upregulation in colon cancer cells.Proteasome inhibition blocks necroptosis by attenuating death complex aggregation.Dasatinib promotes TRAIL-mediated apoptosis by upregulating CHOP-dependent death receptor 5 in gastric cancer.
P2860
Q37427124-F1923C97-78B8-4222-B960-1CF4E5C1C09AQ37687457-5E18BA89-112F-4B95-8626-59FCF414EDE3Q37708954-F41032CD-7C4F-49B4-B7C4-0173B0204D85Q38703639-B5F0A86D-8B04-4A14-ABA4-5B088FA555D9Q38800788-DB0EA418-4A13-4E2B-B1B1-52F377C6564BQ41233246-ACAF8221-0C39-4D11-87C5-F20DBD7C70D4Q41387467-EC0C0261-C337-4D42-863B-7EFBF61B4016Q47141630-D97FF087-1392-40B8-90A0-DC8066AC7CEEQ47161019-45094DC5-67E3-48EE-AB35-7A4674B0CCDCQ52370139-BEE06911-5AAD-4690-95CC-67F643822F2CQ54111073-A67DDF24-EB90-4811-A57A-6A20ECB44A0E
P2860
The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5
description
2015 nî lūn-bûn
@nan
2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The novel proteasome inhibitor ...... bilization of death receptor 5
@ast
The novel proteasome inhibitor ...... bilization of death receptor 5
@en
The novel proteasome inhibitor ...... bilization of death receptor 5
@nl
type
label
The novel proteasome inhibitor ...... bilization of death receptor 5
@ast
The novel proteasome inhibitor ...... bilization of death receptor 5
@en
The novel proteasome inhibitor ...... bilization of death receptor 5
@nl
prefLabel
The novel proteasome inhibitor ...... bilization of death receptor 5
@ast
The novel proteasome inhibitor ...... bilization of death receptor 5
@en
The novel proteasome inhibitor ...... bilization of death receptor 5
@nl
P2093
P2860
P356
P1433
P1476
The novel proteasome inhibitor ...... bilization of death receptor 5
@en
P2093
Fadlo R Khuri
Jiusheng Deng
Shaohua Li
Shi-Yong Sun
Weilong Yao
You-Take Oh
P2860
P304
17532-17542
P356
10.18632/ONCOTARGET.3947
P407
P577
2015-07-01T00:00:00Z