Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels
about
Water wires in atomistic models of the Hv1 proton channelMolecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channelsOutward Rectification of Voltage-Gated K+ Channels Evolved at Least Twice in Life HistoryA Gating Charge Transfer Center in Voltage SensorsSolution Structure and Phospholipid Interactions of the Isolated Voltage-Sensor Domain from KvAPThe crystal structure of a voltage-gated sodium channelProtein sectors: evolutionary units of three-dimensional structureProbing the energy landscape of activation gating of the bacterial potassium channel KcsATowards structural systems pharmacology to study complex diseases and personalized medicineProtein sectors: statistical coupling analysis versus conservationEvolution-Based Functional Decomposition of ProteinsFeeling the hidden mechanical forces in lipid bilayer is an original senseHot spots for allosteric regulation on protein surfacesCooperative activation of the T-type CaV3.2 channel: interaction between Domains II and III.Characterization of the gating brake in the I-II loop of CaV3 T-type calcium channels.Ins and outs of T-channel structure function.The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel.Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore openingThe S1 helix critically regulates the finely tuned gating of Kv11.1 channelsReduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling.Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of IKs.Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channelBK channel activation: structural and functional insightsIon channel voltage sensors: structure, function, and pathophysiology.Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anestheticsImportance of lipid-pore loop interface for potassium channel structure and function.Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels.Inter-subunit interactions across the upper voltage sensing-pore domain interface contribute to the concerted pore opening transition of Kv channels.Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channelMolecular mapping of general anesthetic sites in a voltage-gated ion channel.A specialized molecular motion opens the Hv1 voltage-gated proton channel.A molecular framework for temperature-dependent gating of ion channelsComparative sequence analysis suggests a conserved gating mechanism for TRP channels.Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.A theoretical model for calculating voltage sensitivity of ion channels and the application on Kv1.2 potassium channel.Coupling between the voltage-sensing and pore domains in a voltage-gated potassium channel.Opposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels.Coupling of voltage-sensors to the channel pore: a comparative viewMigration of PIP2 lipids on voltage-gated potassium channel surface influences channel deactivationK⁺ conduction and Mg²⁺ blockade in a shaker Kv-channel single point mutant with an unusually high conductance
P2860
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P2860
Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@ast
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@en
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@nl
type
label
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@ast
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@en
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@nl
prefLabel
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@ast
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@en
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@nl
P2860
P50
P3181
P1433
P1476
Two separate interfaces betwee ...... oltage-dependent K(+) channels
@en
P2093
Seok-Yong Lee
P2860
P3181
P356
10.1371/JOURNAL.PBIO.1000047
P407
P577
2009-03-03T00:00:00Z