p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system
about
The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2Structure of p73 DNA-binding domain tetramer modulates p73 transactivationTransactivation specificity is conserved among p53 family proteins and depends on a response element sequence codeJNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stressQuantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Tumor protein p53 (TP53) testing and Li-Fraumeni syndrome : current status of clinical applications and future directions.Identification of new p53 target microRNAs by bioinformatics and functional analysisEvolution of p53 transactivation specificity through the lens of a yeast-based functional assayNew insights into cancer-related proteins provided by the yeast model.Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.EEC- and ADULT-associated TP63 mutations exhibit functional heterogeneity toward P63 responsive sequences.Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.Dual fluorescent protein-based bioassay system for the detection of genotoxic chemical substances in Saccharomyces cerevisiae.The CDKN2A/p16(INK) (4a) 5'UTR sequence and translational regulation: impact of novel variants predisposing to melanoma.p53, p63 and p73 in the wonderland of S. cerevisiae.Novel simplified yeast-based assays of regulators of p53-MDMX interaction and p53 transcriptional activity.TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear.Etoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation
P2860
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P2860
p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
p53 transactivation and the im ...... d yeast-based screening system
@ast
p53 transactivation and the im ...... d yeast-based screening system
@en
p53 transactivation and the im ...... d yeast-based screening system
@nl
type
label
p53 transactivation and the im ...... d yeast-based screening system
@ast
p53 transactivation and the im ...... d yeast-based screening system
@en
p53 transactivation and the im ...... d yeast-based screening system
@nl
prefLabel
p53 transactivation and the im ...... d yeast-based screening system
@ast
p53 transactivation and the im ...... d yeast-based screening system
@en
p53 transactivation and the im ...... d yeast-based screening system
@nl
P2093
P2860
P50
P1433
P1476
p53 transactivation and the im ...... d yeast-based screening system
@en
P2093
Alberto Inga
Jennifer Jordan
Mattia Lion
P2860
P304
P356
10.1371/JOURNAL.PONE.0020643
P407
P50
P577
2011-06-02T00:00:00Z