EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity - Wikidata - thesis-toulmin - TriplyDB

EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity

EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity

http://www.wikidata.org/entity/Q28486742

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Evolutionary landscape of the Mycobacterium tuberculosis complex from the viewpoint of PhoPR: implications for virulence regulation and application to vaccine development The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10 Structural and biochemical characterization of the essential DsbA-like disulfide bond forming protein from Mycobacterium tuberculosis Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c Comparison of four different crystal forms of theMycobacterium tuberculosisESX-1 secreted protein regulator EspR Simultaneous analysis of multiple Mycobacterium tuberculosis knockdown mutants in vitro and in vivo Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.Mycobacterial Esx-3 requires multiple components for iron acquisition.A novel ESX-1 locus reveals that surface-associated ESX-1 substrates mediate virulence in Mycobacterium marinum.An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology Dimer recognition and secretion by the ESX secretion system in Bacillus subtilis Correlation of phenotypic profiles using targeted proteomics identifies mycobacterial esx-1 substrates.Homeostasis of N-α-terminal acetylation of EsxA correlates with virulence in Mycobacterium marinum.Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.Regulated Expression Systems for Mycobacteria and Their Applications Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.The ESX system in Bacillus subtilis mediates protein secretion.Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.Long-range transcriptional control of an operon necessary for virulence-critical ESX-1 secretion in Mycobacterium tuberculosis.Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response.Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence.The MprB extracytoplasmic domain negatively regulates activation of the Mycobacterium tuberculosis MprAB two-component system.Evolutionary Thrift: Mycobacteria Repurpose Plasmid Diversity during Adaptation of Type VII Secretion Systems.Challenges and opportunities in developing novel drugs for TB.Virulence factors of the Mycobacterium tuberculosis complex Antigen-specific CD8(+) T cells and protective immunity to tuberculosis.Functional analysis of the EspR binding sites upstream of espR in Mycobacterium tuberculosis.Release of mycobacterial antigens.Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.Esx Systems and the Mycobacterial Cell Envelope: What's the Connection?ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria.EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP.

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EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity

http://www.wikidata.org/entity/Q28486742

description

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2010

@ast

im Juni 2010 veröffentlichter wissenschaftlicher Artikel

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scientific journal article

@en

vedecký článok (publikovaný 2010/06/24)

@sk

vědecký článek publikovaný v roce 2010

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wetenschappelijk artikel (gepubliceerd op 2010/06/24)

@nl

наукова стаття, опублікована в червні 2010

@uk

مقالة علمية (نشرت في 24-6-2010)

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name

EspA acts as a critical mediat ...... bacterial cell wall integrity

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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type

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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prefLabel

EspA acts as a critical mediat ...... bacterial cell wall integrity

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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JOURNAL.PPAT.1000957

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EspA acts as a critical mediat ...... bacterial cell wall integrity

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Alejandra Garces

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Alissa C. Rothchild

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Bryan Krastins

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David A. Sarracino

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Joshua S. Woodworth

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Krishnamohan Atmakuri

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Mary F. Lopez

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Michael R. Chase

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Samuel M. Behar

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Sarah M. Fortune

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Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria

Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor

A statistical model for identifying proteins by tandem mass spectrometry

Detecting differential and correlated protein expression in label-free shotgun proteomics

Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages

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10.1371/JOURNAL.PPAT.1000957

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Akafuba bulwadde

Mycobacterium tuberculosis

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2891827

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