Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
about
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic inventionC-terminal phosphorylation controls the stability and function of p27kip1Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcriptionRegulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteinsTransforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsTransforming growth factor-beta, transforming growth factor-beta receptor II, and p27Kip1 expression in nontumorous and neoplastic human pituitariesSpecialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factorIncreased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell lineMASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activationTherapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure.HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleusCharacterization of the cullin and F-box protein partner Skp1Identification of functional domains in the neuronal Cdk5 activator proteinInhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit.Critical differences between isoforms of securin reveal mechanisms of separase regulationSalt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers.Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1.Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27Regulation of the G1 phase of the mammalian cell cycle.Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependencyAnalysis of cyclin D3-cdk4 complexes in fibroblasts expressing and lacking p27(kip1) and p21(cip1).Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 functionMechanisms of cyclin-dependent kinase inactivation by progestinsParadigms of growth control: relation to Cdk activation.Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT.p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes.Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).Density-dependent growth inhibition of fibroblasts ectopically expressing p27(kip1)Brain-derived neurotrophic factor-dependent cdk1 inhibition prevents G2/M progression in differentiating tetraploid neurons.Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1.Screening of cell cycle fusion proteins to identify kinase signaling networksProtein expression of the cell-cycle inhibitor p27Kip1 in malignant melanoma: inverse correlation with disease-free survival.
P2860
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P2860
Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
description
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im September 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/09/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/09/01)
@nl
наукова стаття, опублікована у вересні 1995
@uk
научни чланак (објављен 1995/09/01)
@sr
name
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@ast
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@en
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@nl
type
label
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@ast
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@en
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@nl
prefLabel
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@ast
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@en
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@nl
P2093
P2860
P3181
P356
P1476
Redistribution of the CDK inhi ...... tin or ultraviolet irradiation
@en
P2093
H. Toyoshima
R. Y. Poon
P2860
P304
P3181
P356
10.1091/MBC.6.9.1197
P577
1995-09-01T00:00:00Z