Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
about
beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteinsIdentification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysisPR72, a novel regulator of Wnt signaling required for Naked cuticle functionMyristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membraneRegulation of the Wnt signaling pathway by disabled-2 (Dab2)Identification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathwayNaked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells.EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradationPR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticleMyristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cellsIdentification of novel rare mutations of DACT1 in human neural tube defectsThe ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signalingWnt signalling in lung development and diseasesDirect binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of FrizzledChanges in gene expression foreshadow diet-induced obesity in genetically identical miceNaked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-cateninThe loss of glypican-3 induces alterations in Wnt signalingCasein kinase Iepsilon modulates the signaling specificities of dishevelledPosterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streakWnt3a links left-right determination with segmentation and anteroposterior axis elongation.Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumorsLrp6 is required for convergent extension during Xenopus gastrulation.Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signalingDown-regulation of NKD1 increases the invasive potential of non-small-cell lung cancer and correlates with a poor prognosis.Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors.Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterningConvergence between Wnt-β-catenin and EGFR signaling in cancer.Increasingly complex: new players enter the Wnt signaling network.Wnt signalling in adenomas of familial adenomatous polyposis patients.A targeted mutation of Nkd1 impairs mouse spermatogenesis.An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle.Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling.Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors.Nkd1 functions as a passive antagonist of Wnt signaling.The Wnt antagonist sFRP1 as a favorable prognosticator in human biliary tract carcinoma.Structural studies of human Naked2: a biologically active intrinsically unstructured protein.Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma.Wnt ligand-dependent activation of the negative feedback regulator Nkd1.
P2860
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P2860
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
description
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2001
@ast
im März 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/03/27)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/03/27)
@nl
наукова стаття, опублікована в березні 2001
@uk
name
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@ast
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@en
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@nl
type
label
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@ast
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@en
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@nl
prefLabel
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@ast
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@en
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@nl
P2093
P2860
P356
P1476
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
@en
P2093
A. M. Nelson
C. Reinhard
C. Sakanaka
J. B. Wallingford
L. T. Williams
R. M. Harland
W. J. Fantl
P2860
P304
P356
10.1073/PNAS.071041898
P407
P577
2001-03-27T00:00:00Z