Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
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The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed siteβ-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradationAdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiencySkeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contractionGenes, diet and type 2 diabetes mellitus: a reviewRetinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodiesThe role of genes involved in lipolysis on weight loss program in overweight and obese individualsComparative gene identification-58/α/β hydrolase domain 5: more than just an adipose triglyceride lipase activator?Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectorsOn the formation of lipid droplets in human adipocytes: the organization of the perilipin-vimentin cortexLipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cellsThe perilipin homologue, lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep lossPerilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytesChronic alcohol consumption potentiates the development of diabetes through pancreatic β-cell dysfunctionThe Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose CellsThe cell biology of fat expansionLipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysisDepot-specific differences in perilipin mRNA but not protein expression in obesityADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cellsRegulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell linePolymorphisms in PLIN and hypertension combined with obesity and lipid profiles in Han ChineseGender-specific association of a perilipin gene haplotype with obesity risk in a white populationSequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivoCOPI complex is a regulator of lipid homeostasisMesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balancePerilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidationActivation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteinsCardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunctionIdentification of mouse Prp19p as a lipid droplet-associated protein and its possible involvement in the biogenesis of lipid dropletsResistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 miceThe orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expressionThe life of lipid dropletsProteomic insights into an expanded cellular role for cytoplasmic lipid droplets.Lipid Droplets in Health and Disease.Piecing together the puzzle of perilipin proteins and skeletal muscle lipolysis.Role of Receptor-Interacting Protein 140 in human fat cellsDepot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obeseDifferential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in miceRNA interference silencing of a major lipid droplet protein affects lipid droplet size in Chlamydomonas reinhardtii.The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure.
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P2860
Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity
description
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2001
@ast
im Mai 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/05/22)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/05/22)
@nl
наукова стаття, опублікована в травні 2001
@uk
name
Perilipin ablation results in ...... stance to diet-induced obesity
@ast
Perilipin ablation results in ...... stance to diet-induced obesity
@en
Perilipin ablation results in ...... stance to diet-induced obesity
@nl
type
label
Perilipin ablation results in ...... stance to diet-induced obesity
@ast
Perilipin ablation results in ...... stance to diet-induced obesity
@en
Perilipin ablation results in ...... stance to diet-induced obesity
@nl
prefLabel
Perilipin ablation results in ...... stance to diet-induced obesity
@ast
Perilipin ablation results in ...... stance to diet-induced obesity
@en
Perilipin ablation results in ...... stance to diet-induced obesity
@nl
P2093
P2860
P3181
P356
P1476
Perilipin ablation results in ...... stance to diet-induced obesity
@en
P2093
A. R. Kimmel
C. Sztalryd
C. X. Deng
D. L. Roush
J. Gruia-Gray
J. T. Tansey
M. L. Reitman
P2860
P304
P3181
P356
10.1073/PNAS.101042998
P407
P577
2001-05-22T00:00:00Z