Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway
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Neurotrophin-regulated signalling pathwaysTargeting RTK Signaling Pathways in CancerMEK5/ERK5 pathway: the first fifteen yearsERK5 and Cell Proliferation: Nuclear Localization Is What MattersERK5 Mediated Signalling in Diabetic RetinopathyMitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complexExtracellular Signal-Regulated Kinase 5 is Required for Low-Concentration H2O2-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells.Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells.Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectivesDevelopment and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.WNK kinases influence TRPV4 channel function and localization.ERK5 signalling in prostate cancer promotes an invasive phenotype.Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate.Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb.Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cellsThe MAPK ERK5, but not ERK1/2, inhibits the progression of monocytic phenotype to the functioning macrophage.Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinomap90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memoryInducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesisRegulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathwayConditional Inhibition of Adult Neurogenesis by Inducible and Targeted Deletion of ERK5 MAP Kinase Is Not Associated with Anxiety/Depression-Like Behaviors(1,2).Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation.MAPK signalling: ERK5 versus ERK1/2.ERK5 promotes Src-induced podosome formation by limiting Rho activation.MKK signaling and vascularization.Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.Targeting the PI3K and MAPK pathways to treat Kaposi's-sarcoma-associated herpes virus infection and pathogenesis.Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.Mitogen-activated protein kinases in heart development and diseasesKey signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development.Inhibition of histone acetylation by curcumin reduces alcohol-induced fetal cardiac apoptosis.Role of extracellular signal-regulated kinase 5 in adipocyte signaling.Cytoskeletal protein kinases: titin and its relations in mechanosensing.ERK5 and its role in tumour development.The role of ERK5 in endothelial cell function.Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.A novel mitogen-activated protein kinase docking site in the N terminus of MEK5alpha organizes the components of the extracellular signal-regulated kinase 5 signaling pathway.
P2860
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P2860
Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
@sq
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت عام 2005)
@ar
মলিকুলার অ্যাণ্ড সেলুলার বায়োলজি নামক বৈজ্ঞানিক পত্রিকায় প্রকাশিত নিবন্ধ
@bn
name
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@ast
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@en
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@nl
type
label
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@ast
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@en
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@nl
prefLabel
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@ast
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@en
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@nl
P2093
P2860
P3181
P1476
Targeted deletion of mek5 caus ...... factor 2 cell survival pathway
@en
P2093
Anita J. Merritt
Cathy Tournier
Elizabeth J. Cartwright
Emmanouil S. Papadakis
Jan Seyfried
Jill Dixon
Katherine G. Finegan
Midori Kayahara
Raymond P. Boot-Handford
P2860
P304
P3181
P356
10.1128/MCB.25.1.336-345.2005
P407
P577
2005-01-01T00:00:00Z