Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation
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Investigating the transcriptional control of cardiovascular developmentA Murine Myh6MerCreMer Knock-In Allele Specifically Mediates Temporal Genetic Deletion in Cardiomyocytes after Tamoxifen InductionFoxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septationRbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation.Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node.Heart fields and cardiac morphogenesisSingle-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo.A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation.BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesisConvergent evolutionary reduction of atrial septation in lungless salamandersGenetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous PoleTbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation.Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel.Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population.Wnt/β-catenin and sonic hedgehog pathways interact in the regulation of the development of the dorsal mesenchymal protrusion.Growth arrest specific 1 (GAS1) is abundantly expressed in the adult mouse central nervous systemExpression of the BMP receptor Alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation.Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.The Dorsal Mesenchymal Protrusion and the Pathogenesis of Atrioventricular Septal Defects.Inhibition of Gata4 and Tbx5 by Nicotine-Mediated DNA Methylation in Myocardial Differentiation.A molecular and genetic outline of cardiac morphogenesis.Signaling and transcriptional networks in heart development and regeneration.Cardiac Embryology and Molecular Mechanisms of Congenital Heart Disease: A Primer for Anesthesiologists.Emerging Field of Cardiomics: High-Throughput Investigations into Transcriptional Regulation of Cardiovascular Development and Disease.KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.TBX5: A Key Regulator of Heart Development.A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells.Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation.Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development.Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis.Mutations in Hnrnpa1 cause congenital heart defects.Osr1 functions downstream of Hedgehog pathway to regulate foregut development.nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression.A right-handed signalling pathway drives heart looping in vertebrates.Fate mapping of Trps1 daughter cells during cardiac development using novel Trps1-Cre mice.Heterozygous loss-of-function mutation in Odd-skipped related 1 (Osr1) is associated with vesicoureteric reflux, duplex systems, and hydronephrosis.GATA6 Regulates Aortic Valve Remodeling and its Haploinsufficiency Leads to RL-Type Bicuspid Aortic Valve.
P2860
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P2860
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation
description
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im August 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/08/14)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/08/14)
@nl
наукова стаття, опублікована в серпні 2012
@uk
مقالة علمية (نشرت في 14-8-2012)
@ar
name
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@ast
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@en
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@nl
type
label
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@ast
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@en
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@nl
prefLabel
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@ast
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@en
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@nl
P2093
P2860
P3181
P1433
P1476
Tbx5-hedgehog molecular networ ...... art field for atrial septation
@en
P2093
Andrew D. Hoffmann
Ivan P. Moskowitz
Joshua M. Friedland-Little
Linglin Xie
Ozanna Burnicka-Turek
P2860
P304
P3181
P356
10.1016/J.DEVCEL.2012.06.006
P407
P577
2012-08-14T00:00:00Z