SOX9 is required for maintenance of the pancreatic progenitor cell pool
about
In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human isletsSOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epitheliumControl of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factorsβ-Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreasLiver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseasesMultipotent pancreas progenitors: Inconclusive but pivotal topicNotch Signaling in Pancreatic DevelopmentDevelopmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular OriginGenes involved in pancreatic islet cell rejuvenationPancreatic stem cells remain unresolvedPancreatic ductal cells in development, regeneration, and neoplasiaRapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryosPancreatic mesenchyme regulates epithelial organogenesis throughout developmentSox9b is a key regulator of pancreaticobiliary ductal system developmentSOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Therapeutic potential of targeting acinar cell reprogramming in pancreatic cancerNatural history of β-cell adaptation and failure in type 2 diabetesTranscription factor regulation of pancreatic organogenesis, differentiation and maturationReversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cellsInsulin receptor substrate-1 deficiency promotes apoptosis in the putative intestinal crypt stem cell region, limits Apcmin/+ tumors, and regulates Sox9Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreasvon Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulationLoss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mousePtf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanismA dosage-dependent requirement for Sox9 in pancreatic endocrine cell formationSox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleusSox9 plays multiple roles in the lung epithelium during branching morphogenesisSox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epitheliumIntrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell PhenotypeLong-term consequences of Sox9 depletion on inner ear development.Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing β-cells.Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.Artificial three-dimensional niches deconstruct pancreas development in vitro.Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and cultureFGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner.Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during developmentInteraction between Hhex and SOX13 modulates Wnt/TCF activitySEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.
P2860
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P2860
SOX9 is required for maintenance of the pancreatic progenitor cell pool
description
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2007
@ast
im Februar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/02/06)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/02/06)
@nl
наукова стаття, опублікована в лютому 2007
@uk
name
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@ast
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@en
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@nl
type
label
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@ast
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@en
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@nl
prefLabel
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@ast
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@en
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@nl
P2093
P2860
P50
P3181
P356
P1476
SOX9 is required for maintenance of the pancreatic progenitor cell pool
@en
P2093
Erin E. Mayes
Gerd Scherer
Kristine K. Freude
Maike Sander
Man N. Tran
P2860
P304
P3181
P356
10.1073/PNAS.0609217104
P407
P577
2007-02-06T00:00:00Z